Engineering of a redox protein for DNA-directed assembly

Geza Szilvay; Shayna Brocato; Dmitri Ivnitski; Carol Li; Pablo De La Iglesia; Carolin Lau; Eva Chi; Margaret Werner-Washburne; Scott Banta; Plamen Atanassov

doi:10.1039/C1CC11951F

Engineering of a redox protein for DNA-directed assembly

Geza Szilvay, Shayna Brocato, Dmitri Ivnitski, Carol Li, Pablo De La Iglesia, Carolin Lau, Eva Chi, Margaret Werner-Washburne, Scott Banta, Plamen Atanassov^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

6 Citations (Scopus)

Abstract

Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.

Original language	English
Pages (from-to)	7464-7466
Journal	Chemical Communications
Volume	47
Issue number	26
DOIs	https://doi.org/10.1039/C1CC11951F
Publication status	Published - 2011
MoE publication type	A1 Journal article-refereed

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10.1039/C1CC11951F

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title = "Engineering of a redox protein for DNA-directed assembly",

abstract = "Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.",

author = "Geza Szilvay and Shayna Brocato and Dmitri Ivnitski and Carol Li and {De La Iglesia}, Pablo and Carolin Lau and Eva Chi and Margaret Werner-Washburne and Scott Banta and Plamen Atanassov",

year = "2011",

doi = "10.1039/C1CC11951F",

language = "English",

volume = "47",

pages = "7464--7466",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry RSC",

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T1 - Engineering of a redox protein for DNA-directed assembly

AU - Szilvay, Geza

AU - Brocato, Shayna

AU - Ivnitski, Dmitri

AU - Li, Carol

AU - De La Iglesia, Pablo

AU - Lau, Carolin

AU - Chi, Eva

AU - Werner-Washburne, Margaret

AU - Banta, Scott

AU - Atanassov, Plamen

PY - 2011

Y1 - 2011

N2 - Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.

AB - Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.

U2 - 10.1039/C1CC11951F

DO - 10.1039/C1CC11951F

M3 - Article

SN - 1359-7345

VL - 47

SP - 7464

EP - 7466

JO - Chemical Communications

JF - Chemical Communications

IS - 26

ER -

Engineering of a redox protein for DNA-directed assembly

Abstract

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