Engineering of a redox protein for DNA-directed assembly

Geza Szilvay; S. Brocato; D. Ivnitski; C. Li; P. De La Iglesia; C. Lau; E. Chi; M. Werner-Washburne; S. Banta; P. Atanassov

doi:10.1039/C1CC11951F

Engineering of a redox protein for DNA-directed assembly

Geza Szilvay, S. Brocato, D. Ivnitski, C. Li, P. De La Iglesia, C. Lau, E. Chi, M. Werner-Washburne, S. Banta, P. Atanassov (Corresponding Author)

Columbia University

Research output: Contribution to journal › Article › Scientific › peer-review

6 Citations (Scopus)

Abstract

Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.

Original language	English
Pages (from-to)	7464-7466
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	26
DOIs	https://doi.org/10.1039/C1CC11951F
Publication status	Published - 2011
MoE publication type	A1 Journal article-refereed

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title = "Engineering of a redox protein for DNA-directed assembly",

abstract = "Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.",

author = "Geza Szilvay and S. Brocato and D. Ivnitski and C. Li and {De La Iglesia}, P. and C. Lau and E. Chi and M. Werner-Washburne and S. Banta and P. Atanassov",

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doi = "10.1039/C1CC11951F",

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T1 - Engineering of a redox protein for DNA-directed assembly

AU - Szilvay, Geza

AU - Brocato, S.

AU - Ivnitski, D.

AU - Li, C.

AU - De La Iglesia, P.

AU - Lau, C.

AU - Chi, E.

AU - Werner-Washburne, M.

AU - Banta, S.

AU - Atanassov, P.

PY - 2011

Y1 - 2011

N2 - Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.

AB - Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.

U2 - 10.1039/C1CC11951F

DO - 10.1039/C1CC11951F

M3 - Article

SN - 1359-7345

VL - 47

SP - 7464

EP - 7466

JO - Chemical Communications

JF - Chemical Communications

IS - 26

ER -

Engineering of a redox protein for DNA-directed assembly

Abstract

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