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Engineering of a redox protein for DNA-directed assembly

  • Geza Szilvay
  • , Shayna Brocato
  • , Dmitri Ivnitski
  • , Carol Li
  • , Pablo De La Iglesia
  • , Carolin Lau
  • , Eva Chi
  • , Margaret Werner-Washburne
  • , Scott Banta
  • , Plamen Atanassov*
  • *Corresponding author for this work
    • Columbia University
    • University of New Mexico

    Research output: Contribution to journalArticleScientificpeer-review

    Abstract

    Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.
    Original languageEnglish
    Pages (from-to)7464-7466
    JournalChemical Communications
    Volume47
    Issue number26
    DOIs
    Publication statusPublished - 2011
    MoE publication typeA1 Journal article-refereed

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