The concept of the “smart city” has become popular in scientific literature and international policies in the past two decades. Smart cities are known as a system of physical infrastructure, the ICT infrastructure and the social infrastructure exchanging information that flow between its many different subsystems. The “smart cities” concept has been introduced with various dimensions among those, the embedded ICT infrastructure in smart cities is playing a decisive role among the functions of the system. One of the important derivatives of ICT is the new communication mediums known as Social Network Services (SNSs) which is emerging and introducing additional functionalities to “smart cities”. This paper seeks to advance the understanding of SNSs in smart cities for evaluating the effects on the innovation and entrepreneurial ecosystem. This agenda has been tackled by a rigorous methodological approach in order to capture and evaluate the presence of entrepreneurial oriented discussion in a popular SNSs medium (Twitter).