Abstract
| Original language | English |
|---|---|
| Title of host publication | Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury |
| Editors | Kenneth V. Honn, Lawrence J. Marnett, Santosh Nigam, Edward A. Dennis |
| Publisher | Springer |
| ISBN (Electronic) | 978-1-4615-4793-8 |
| ISBN (Print) | 978-1-4613-7171-7 |
| DOIs | |
| Publication status | Published - 2000 |
| MoE publication type | A3 Part of a book or another research book |
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Evidence for a carbocation intermediate in the enzymatic transformation of leukotriene A4 into leukotriene B4. / Andberg, M.; Hamberg, M.; Haeggström, J.Z.
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury. ed. / Kenneth V. Honn; Lawrence J. Marnett; Santosh Nigam; Edward A. Dennis. Springer, 2000. (Advances in Experimental Medicine and Biology, Vol. 469).Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Scientific › peer-review
TY - CHAP
T1 - Evidence for a carbocation intermediate in the enzymatic transformation of leukotriene A4 into leukotriene B4
AU - Andberg, M.
AU - Hamberg, M.
AU - Haeggström, J.Z.
PY - 2000
Y1 - 2000
N2 - Leukotriene (LT) A4 hydrolase is a soluble enzyme that catalyzes the production of 5S,12R-dihydroxy-6, 14-cis-8,10-trans-eicosatetraenoic acid (LTB4) from the transient allylic epoxide 5S-trans-5, 6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid (LTA4). LTB4 elicits chemotaxis and adherence of leukocytes in only nM concentrations and is regarded as an important chemical mediator in a variety of inflammatory disorders.
AB - Leukotriene (LT) A4 hydrolase is a soluble enzyme that catalyzes the production of 5S,12R-dihydroxy-6, 14-cis-8,10-trans-eicosatetraenoic acid (LTB4) from the transient allylic epoxide 5S-trans-5, 6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid (LTA4). LTB4 elicits chemotaxis and adherence of leukocytes in only nM concentrations and is regarded as an important chemical mediator in a variety of inflammatory disorders.
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-0034463359&partnerID=MN8TOARS
U2 - 10.1007/978-1-4615-4793-8_47
DO - 10.1007/978-1-4615-4793-8_47
M3 - Chapter or book article
SN - 978-1-4613-7171-7
BT - Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury
A2 - Honn, Kenneth V.
A2 - Marnett, Lawrence J.
A2 - Nigam, Santosh
A2 - Dennis, Edward A.
PB - Springer
ER -