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Exocytosis requires asymmetry in the central layer of the SNARE complex
Rainer Ossig
, Hans Schmitt
, Bert de Groot
, Dietmar Riedel
, Sirkka Keränen
, Hans Ronne
, Helmut Grubmuller
, Reinhard Jahn
*
*
Corresponding author for this work
VTT Technical Research Centre of Finland
Max Planck Society
University of Münster
VTT (former employee or external)
Swedish University of Agricultural Sciences
Research output
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Contribution to journal
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Article
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Scientific
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peer-review
65
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Keyphrases
Exocytosis
100%
Attachment Protein
100%
Receptor Complex
100%
Protein Receptor
100%
Helix
40%
Membrane Fusion
40%
Cell Growth
20%
Molecular Dynamics
20%
Cell Wall Proteins
20%
Leucine
20%
Glutamine
20%
Additional mutations
20%
Protein Secretion
20%
Eukaryotic Cells
20%
Functional Consequences
20%
Arginine
20%
Asymmetric Pattern
20%
Normal Function
20%
Free Energy Perturbation
20%
Synaptic
20%
Polar Amino Acids
20%
INIS
layers
100%
proteins
100%
asymmetry
100%
receptors
100%
membranes
33%
secretion
33%
simulation
16%
yeasts
16%
leucine
16%
length
16%
growth
16%
molecular dynamics method
16%
free energy
16%
defects
16%
perturbations
16%
amino acids
16%
mutations
16%
mirrors
16%
glutamine
16%
arginine
16%
Immunology and Microbiology
Membrane Fusion
100%
Exocytosis
100%
Dynamics
50%
Secretion (Process)
50%
Protein Secretion
50%
Energy Transfer
50%
Eukaryotic Cell
50%
Cell Growth
50%
Amino Acid
50%
Glutamine
50%
Leucine
50%
Arginine
50%
Biochemistry, Genetics and Molecular Biology
Membrane Fusion
100%
Exocytosis
100%
Leucine
50%
Dynamics
50%
Amino Acids
50%
Glutamine
50%
Energy Transfer
50%
Secretion (Process)
50%
Protein Secretion
50%
Cell Growth
50%
Arginine
50%
Medicine and Dentistry
Receptor Protein
100%
Exocytosis
100%
Helix
40%
Membrane Fusion
40%
Leucine
20%
Cell Growth
20%
Protein Secretion
20%
Secretion (Process)
20%
Energy Transfer
20%
Eukaryotic Cell
20%
Cell Protein
20%
Amino Acid
20%
Mathematics
Asymmetric
100%
Middle Layer
100%
Concludes
50%
Energetics
50%
Normal Function
50%