Keyphrases
Glycosidic Bond
100%
Metabolism
100%
Prodrug
100%
Floxuridine
100%
Amino Acid Ester Prodrug
100%
Caco-2 Permeability
100%
5-fluorouridine
85%
Peptide Transporter 1 (PepT1)
85%
HeLa
42%
Thymidine Phosphorylase
42%
Overexpressing
14%
Uptake Studies
14%
High Chemical Stability
14%
Caco-2 Cells
14%
Enzymatic Stability
14%
Bond Cleavage
14%
HeLa Cells
14%
Human Plasma
14%
Caco-2 Cell Monolayer
14%
Intestinal Absorption
14%
Monoesters
14%
Sarcosine
14%
Enzymatic Activation
14%
Oligopeptide Transporter
14%
5-fluorouracil (5-FU)
14%
Therapeutic Index
14%
Caco-2 Transport
14%
Oral Therapeutics
14%
Hydrolytic Stability
14%
Gastrointestinal Resistance
14%
Uptake Inhibition
14%
Oral Delivery
14%
INIS
esters
100%
permeability
100%
metabolism
100%
amino acids
100%
deoxyuridine
100%
uptake
66%
stability
50%
phosphorylases
50%
thymidine
50%
comparative evaluations
33%
transport
33%
plasma
16%
inhibition
16%
delivery
16%
humans
16%
cleavage
16%
hela cells
16%
intestinal absorption
16%
homogenates
16%
uracils
16%
sarcosine
16%
Pharmacology, Toxicology and Pharmaceutical Science
Prodrug
100%
Amino Acid
100%
Glycosidic Bond
100%
Floxuridine
100%
Thymidine Phosphorylase
27%
Bond Cleavage
9%
Oligopeptide
9%
Sarcosine
9%
Therapeutic Window
9%
Fluorouracil
9%