Fructose metabolism in Zymomonas mobilis

Liisa Viikari, Matti Korhola

Research output: Contribution to journalArticleScientificpeer-review

34 Citations (Scopus)

Abstract

In the metabolism of fructose by Zymomonas, the ethanol yield is decreased due to the formation of dihydroxyacetone, mannitol and glycerol. The reduction of fructose to mannitol by an NADPH-dependent mannitol dehydrogenase is apparently coupled to the oxidation of glucose-6-phosphate by glucose-6-phosphate dehydrogenase, which exhibits higher activity with NADP than with NAD as cofactor. The relatively low cell yield on fructose can partly be explained by the loss of ATP in the formation of dihydroxyacetone and glycerol and partly by the toxic effect of dihydroxyacetone and acetaldehyde on the growth of the organism.

Original languageEnglish
Pages (from-to)471 - 476
Number of pages6
JournalApplied Microbiology and Biotechnology
Volume24
Issue number6
DOIs
Publication statusPublished - 1986
MoE publication typeNot Eligible

Fingerprint

Dihydroxyacetone
Zymomonas
Fructose
Mannitol
NADP
Glycerol
Mannitol Dehydrogenases
Glucose-6-Phosphate
Acetaldehyde
Glucosephosphate Dehydrogenase
Poisons
NAD
Ethanol
Adenosine Triphosphate
Growth

Cite this

Viikari, Liisa ; Korhola, Matti. / Fructose metabolism in Zymomonas mobilis. In: Applied Microbiology and Biotechnology. 1986 ; Vol. 24, No. 6. pp. 471 - 476.
@article{11931c81578a43a6a190b7e29c52a5e8,
title = "Fructose metabolism in Zymomonas mobilis",
abstract = "In the metabolism of fructose by Zymomonas, the ethanol yield is decreased due to the formation of dihydroxyacetone, mannitol and glycerol. The reduction of fructose to mannitol by an NADPH-dependent mannitol dehydrogenase is apparently coupled to the oxidation of glucose-6-phosphate by glucose-6-phosphate dehydrogenase, which exhibits higher activity with NADP than with NAD as cofactor. The relatively low cell yield on fructose can partly be explained by the loss of ATP in the formation of dihydroxyacetone and glycerol and partly by the toxic effect of dihydroxyacetone and acetaldehyde on the growth of the organism.",
author = "Liisa Viikari and Matti Korhola",
year = "1986",
doi = "10.1007/BF00250326",
language = "English",
volume = "24",
pages = "471 -- 476",
journal = "Applied Microbiology and Biotechnology",
issn = "0175-7598",
publisher = "Springer",
number = "6",

}

Fructose metabolism in Zymomonas mobilis. / Viikari, Liisa; Korhola, Matti.

In: Applied Microbiology and Biotechnology, Vol. 24, No. 6, 1986, p. 471 - 476.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Fructose metabolism in Zymomonas mobilis

AU - Viikari, Liisa

AU - Korhola, Matti

PY - 1986

Y1 - 1986

N2 - In the metabolism of fructose by Zymomonas, the ethanol yield is decreased due to the formation of dihydroxyacetone, mannitol and glycerol. The reduction of fructose to mannitol by an NADPH-dependent mannitol dehydrogenase is apparently coupled to the oxidation of glucose-6-phosphate by glucose-6-phosphate dehydrogenase, which exhibits higher activity with NADP than with NAD as cofactor. The relatively low cell yield on fructose can partly be explained by the loss of ATP in the formation of dihydroxyacetone and glycerol and partly by the toxic effect of dihydroxyacetone and acetaldehyde on the growth of the organism.

AB - In the metabolism of fructose by Zymomonas, the ethanol yield is decreased due to the formation of dihydroxyacetone, mannitol and glycerol. The reduction of fructose to mannitol by an NADPH-dependent mannitol dehydrogenase is apparently coupled to the oxidation of glucose-6-phosphate by glucose-6-phosphate dehydrogenase, which exhibits higher activity with NADP than with NAD as cofactor. The relatively low cell yield on fructose can partly be explained by the loss of ATP in the formation of dihydroxyacetone and glycerol and partly by the toxic effect of dihydroxyacetone and acetaldehyde on the growth of the organism.

U2 - 10.1007/BF00250326

DO - 10.1007/BF00250326

M3 - Article

VL - 24

SP - 471

EP - 476

JO - Applied Microbiology and Biotechnology

JF - Applied Microbiology and Biotechnology

SN - 0175-7598

IS - 6

ER -