Fructose metabolism in Zymomonas mobilis

Liisa Viikari (Corresponding Author), Matti Korhola

Research output: Contribution to journalArticleScientificpeer-review

34 Citations (Scopus)


In the metabolism of fructose by Zymomonas, the ethanol yield is decreased due to the formation of dihydroxyacetone, mannitol and glycerol. The reduction of fructose to mannitol by an NADPH-dependent mannitol dehydrogenase is apparently coupled to the oxidation of glucose-6-phosphate by glucose-6-phosphate dehydrogenase, which exhibits higher activity with NADP than with NAD as cofactor. The relatively low cell yield on fructose can partly be explained by the loss of ATP in the formation of dihydroxyacetone and glycerol and partly by the toxic effect of dihydroxyacetone and acetaldehyde on the growth of the organism.
Original languageEnglish
Pages (from-to)471-476
JournalApplied Microbiology and Biotechnology
Issue number6
Publication statusPublished - 1986
MoE publication typeNot Eligible


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