Gold nanostructures for OCT imaging of capillary flow

Olga Bibikova, Alexey Popov, Alexander Bykov, Artur Prilepskyii, Matti Kinnunen, Krisztián Kordás, Vladimir Bogatyrev, Nikolai Khlebtsov, Valery Tuchin

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

5 Citations (Scopus)


In this paper, plasmon-resonant nanostructures, such as gold nanostars and their silica-coated composites, were used for enhancement of OCT image contrast of water flows in glass capillaries. The contrasting properties of the synthesized nanostars and nanocomposites with silica shell thickness of about 5 nm and 50 nm were compared in the framework of capillary stasis model. The most intensive signal was detected from the nanocomposites with the thickest silica shell. The nanocomposites were characterized by optical spectroscopy and electron microscopy. Nontoxicity of nanostars and nanocomposites up to ~ 3 mg/mL concentration was showed by MTT assay suggesting practical applications of the nanostructures for bioimaging.

Original languageEnglish
Title of host publicationBiophotonics
Subtitle of host publicationPhotonic Solutions for Better Health Care IV
EditorsJürgen Popp, Valery V. Tuchin, Dennis L. Matthews, Francesco Saverio Pavone, Paul Garside
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Print)978-1-6284-1077-8
Publication statusPublished - 1 Jan 2014
MoE publication typeNot Eligible
EventBiophotonics: Photonic Solutions for Better Health Care IV - Brussels, Belgium
Duration: 14 Apr 201417 Apr 2014

Publication series

SeriesProceedings of SPIE




  • gold nanostars
  • gold-silica nanocomposites
  • light scattering
  • optical coherence tomography
  • plasmon-resonant nanoparticles
  • spectroscopy


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