How to study lipidomes

Tuulikki Seppänen-Laakso, Matej Orešič (Corresponding Author)

Research output: Contribution to journalReview ArticleScientificpeer-review

41 Citations (Scopus)

Abstract

Lipidome is loosely defined as the entire spectrum of lipids in a biological system. Given the modern lipidomics platforms for the first time empower us with the ability to obtain a snapshot of complete cellular/organismal lipidome, many surprises and discoveries are likely awaiting us in the area of lipids as related to cellular/organismal physiology. The lipidomics approaches can be applied both as the phenotyping platform and for the hypothesis-driven research aiming to elucidate, e.g., a specific pathway or gene function. Modern lipidomics methods combine the latest mass spectrometry technology and bioinformatics methods with traditional methods such as for sample preparation and lipid extraction.
Original languageEnglish
Pages (from-to)185-190
Number of pages6
JournalJournal of Molecular Endocrinology
Volume42
Issue number3
DOIs
Publication statusPublished - 2009
MoE publication typeA2 Review article in a scientific journal

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Lipids
Computational Biology
Mass Spectrometry
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Genes

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Seppänen-Laakso, Tuulikki ; Orešič, Matej. / How to study lipidomes. In: Journal of Molecular Endocrinology. 2009 ; Vol. 42, No. 3. pp. 185-190.
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How to study lipidomes. / Seppänen-Laakso, Tuulikki; Orešič, Matej (Corresponding Author).

In: Journal of Molecular Endocrinology, Vol. 42, No. 3, 2009, p. 185-190.

Research output: Contribution to journalReview ArticleScientificpeer-review

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T1 - How to study lipidomes

AU - Seppänen-Laakso, Tuulikki

AU - Orešič, Matej

PY - 2009

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AB - Lipidome is loosely defined as the entire spectrum of lipids in a biological system. Given the modern lipidomics platforms for the first time empower us with the ability to obtain a snapshot of complete cellular/organismal lipidome, many surprises and discoveries are likely awaiting us in the area of lipids as related to cellular/organismal physiology. The lipidomics approaches can be applied both as the phenotyping platform and for the hypothesis-driven research aiming to elucidate, e.g., a specific pathway or gene function. Modern lipidomics methods combine the latest mass spectrometry technology and bioinformatics methods with traditional methods such as for sample preparation and lipid extraction.

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DO - 10.1677/JME-08-0150

M3 - Review Article

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SP - 185

EP - 190

JO - Journal of Molecular Endocrinology

JF - Journal of Molecular Endocrinology

SN - 0952-5041

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