In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues

Diana Matthes, Lennart Richter, Jane Müller, Alexander Denisiuk, Sven C. Feifel, Yuquan Xu, Patricia Espinosa-Artiles, Roderich D. Süssmuth (Corresponding Author), István Molnár (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)

Abstract

New beauvericins have been synthesized using the nonribosomal peptide synthetase BbBEAS from the entomopathogenic fungus Beauveria bassiana. Chemical diversity was generated by in vitro chemoenzymatic and in vivo whole cell biocatalytic syntheses using either a B. bassiana mutant or an E. coli strain expressing the bbBeas gene.

Original languageEnglish
Pages (from-to)5674-5676
Number of pages3
JournalChemical Communications
Volume48
Issue number45
DOIs
Publication statusPublished - 9 May 2012
MoE publication typeA1 Journal article-refereed

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