@inproceedings{60a96b54cad34fb084e219969004e863,
title = "In vitro influence of 520 nm diode laser irradiation on red blood cell spontaneous aggregation studied by optical tweezers and light microscopy",
abstract = "The laser has biomodulation effects on blood properties thus could regulate the microcirculation. The laser-RBC interaction mechanism is unclear, whereas most studies provide statistical results and lack detailed observations of laser irradiation effects on blood rheology. This study is designated to probe the in vitro effects of 520 nm diode laser irradiation on red blood cells (RBCs) mutual interaction properties in spontaneous aggregation process in autologous plasma by optical tweezers (OTs), with an attempt to reveal the laser-RBC interaction outcomes at a single-cell level. The results preliminarily show that though the laser irradiation statistically inhibited the increase of the size of RBC aggregates compared with the non-irradiating group, the aggregation force between single RBCs increased slightly with the time of irradiation. ",
keywords = "laser irradiation, light microscopy, optical tweezers, RBC aggregation, Red blood cells (RBCs)",
author = "Ruixue Zhu and Tatiana Avsievich and Alexey Popov and Alexander Bykov and Igor Meglinski",
note = "Funding Information: This work was partially funded by the China Scholarship Council (CSC No. 201706410089, R.Z.). R.Z. acknowledges X.Y. Su (School of Science, Beijing Jiaotong University, Beijing, China) for technical help in laser irradiation source selection. The authors also acknowledge the contribution of Russian Science Foundation (Projects: 19-72-30012 and 20-64-46003). I.M. acknowledges partial support from the Academy of Finland (project 325,097). ; Optical Trapping and Optical Micromanipulation XVIII 2021 ; Conference date: 01-08-2021 Through 05-08-2021",
year = "2021",
doi = "10.1117/12.2595118",
language = "English",
isbn = "978-1-5106-4434-2 ",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "International Society for Optics and Photonics SPIE",
editor = "Kishan Dholakia and Spalding, {Gabriel C.}",
booktitle = "Optical Trapping and Optical Micromanipulation XVIII",
address = "United States",
}