Abstract
Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.
| Original language | English |
|---|---|
| Pages (from-to) | 119-123 |
| Number of pages | 5 |
| Journal | Toxicology Letters |
| Volume | 6 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Jan 1980 |
| MoE publication type | A1 Journal article-refereed |
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Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster. / Penttilä, Merja; Sorsa, Marja; Vainio, Harri.
In: Toxicology Letters, Vol. 6, No. 2, 01.01.1980, p. 119-123.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster
AU - Penttilä, Merja
AU - Sorsa, Marja
AU - Vainio, Harri
PY - 1980/1/1
Y1 - 1980/1/1
N2 - Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.
AB - Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.
UR - http://www.scopus.com/inward/record.url?scp=0018928683&partnerID=8YFLogxK
U2 - 10.1016/0378-4274(80)90178-2
DO - 10.1016/0378-4274(80)90178-2
M3 - Article
C2 - 6774448
AN - SCOPUS:0018928683
VL - 6
SP - 119
EP - 123
JO - Toxicology Letters
JF - Toxicology Letters
SN - 0378-4274
IS - 2
ER -