Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster

Merja Penttilä; Marja Sorsa; Harri Vainio

doi:10.1016/0378-4274(80)90178-2

Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster

Merja Penttilä, Marja Sorsa, Harri Vainio

Not published at VTT

Research output: Contribution to journal › Article › Scientific › peer-review

19 Citations (Scopus)

Abstract

Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.

Original language	English
Pages (from-to)	119-123
Number of pages	5
Journal	Toxicology Letters
Volume	6
Issue number	2
DOIs	https://doi.org/10.1016/0378-4274(80)90178-2
Publication status	Published - 1 Jan 1980
MoE publication type	A1 Journal article-refereed

Access to Document

10.1016/0378-4274(80)90178-2

Cite this

@article{a3442e689e594e7185dfe17dc4872668,

title = "Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster",

abstract = "Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.",

author = "Merja Penttil{\"a} and Marja Sorsa and Harri Vainio",

year = "1980",

month = jan,

day = "1",

doi = "10.1016/0378-4274(80)90178-2",

language = "English",

volume = "6",

pages = "119--123",

journal = "Toxicology Letters",

issn = "0378-4274",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster

AU - Penttilä, Merja

AU - Sorsa, Marja

AU - Vainio, Harri

PY - 1980/1/1

Y1 - 1980/1/1

N2 - Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.

AB - Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was seen in the bone marrow of Chinese hamsters (Cricetulus griseus) injected (i.p.) with a single dose of 1.0 mg/kg b.wt. styrene or with 250 mg/kg b.wt. of the primary metabolite, styrene oxide.

UR - http://www.scopus.com/inward/record.url?scp=0018928683&partnerID=8YFLogxK

U2 - 10.1016/0378-4274(80)90178-2

DO - 10.1016/0378-4274(80)90178-2

M3 - Article

C2 - 6774448

AN - SCOPUS:0018928683

VL - 6

SP - 119

EP - 123

JO - Toxicology Letters

JF - Toxicology Letters

SN - 0378-4274

IS - 2

ER -

Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster

Abstract

Access to Document

Other files and links

Fingerprint

Cite this