Abstract
Growth kinetics and indole alkaloid production ofCatharanthus roseus hairy root cultures were studied in shake flasks and in a small scale fermenter. A logistic growth model commonly used for microbes described well the growth of hairy roots. Of the several parameters analyzed during the cultivation of hairy roots, a linear relationship between sucrose consumption and dry weight increase was obtained. This suggests the validity of sugar analysis as a means in monitoring the growth of hairy roots in fermenters.
Original language | English |
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Pages (from-to) | 519-524 |
Journal | Biotechnology Letters |
Volume | 12 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1990 |
MoE publication type | A1 Journal article-refereed |