Induction of endotoxin of the inflammatory response in the lactating and dry bovine mammary gland

Tiina Mattila (Corresponding Author), Alan Frost

Research output: Contribution to journalArticleScientificpeer-review

14 Citations (Scopus)

Abstract

Quarters of three lactating and three dry cows were infused with 10 μg endotoxin and the inflammatory response induced in the mammary gland was compared. The response of the dry glands was much less than that shown by the lactating glands. The swelling in the lactating quarters was severe after four hours and declined slowly; in the dry quarters the swelling was mild and transient.
Antitrypsin levels, which reflect vascular permeability, were much greater in the lactating quarters, and the somatic cell counts were similarly much higher in the lactating quarters.
One dry quarter gave no response other than a slight increase in antitrypsin after four hours.
Original languageEnglish
Pages (from-to)238-240
JournalResearch in Veterinary Science
Volume46
Issue number2
DOIs
Publication statusPublished - 1989
MoE publication typeA1 Journal article-refereed

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Capillary Permeability
Human Mammary Glands
endotoxins
somatic cell count
blood vessels
Endotoxins
mammary glands
permeability
Cell Count
inflammation
cows
cattle

Cite this

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abstract = "Quarters of three lactating and three dry cows were infused with 10 μg endotoxin and the inflammatory response induced in the mammary gland was compared. The response of the dry glands was much less than that shown by the lactating glands. The swelling in the lactating quarters was severe after four hours and declined slowly; in the dry quarters the swelling was mild and transient. Antitrypsin levels, which reflect vascular permeability, were much greater in the lactating quarters, and the somatic cell counts were similarly much higher in the lactating quarters. One dry quarter gave no response other than a slight increase in antitrypsin after four hours.",
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Induction of endotoxin of the inflammatory response in the lactating and dry bovine mammary gland. / Mattila, Tiina (Corresponding Author); Frost, Alan.

In: Research in Veterinary Science, Vol. 46, No. 2, 1989, p. 238-240.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

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AU - Frost, Alan

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AB - Quarters of three lactating and three dry cows were infused with 10 μg endotoxin and the inflammatory response induced in the mammary gland was compared. The response of the dry glands was much less than that shown by the lactating glands. The swelling in the lactating quarters was severe after four hours and declined slowly; in the dry quarters the swelling was mild and transient. Antitrypsin levels, which reflect vascular permeability, were much greater in the lactating quarters, and the somatic cell counts were similarly much higher in the lactating quarters. One dry quarter gave no response other than a slight increase in antitrypsin after four hours.

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