Influence of multiple light-scattering on TiO2 nanoparticles imbedded into stratum corneum, on light transmittance in UV and visible wavelength regions

Alexey P. Popov, Alexander V. Priezzhev, Jürgen Lademann, Risto Myllylä

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review


This paper focuses on the simulation of propagation of radiation in UV and visible wavelength regions within a superficial skin layer (stratum corneum, SC) partially filled with titanium dioxide (TiO2) nanoparticles. Volume concentrations of the particles (0.67% - 2.25%) correspond to the maximal concentrations of the considered particles in the frames of independent scattering. Transmittance of 307-, 400-, and 500-nm light through a 20-μm thick SC is calculated. The effect of the TiO2 nanoparticles on the contribution of photons undergone different numbers of scattering acts into transmittance is considered. It is shown that administration of the nanoparticles results in the broadening of the distribution of transmitted photons over undergone scattering acts. It also results in the shift of the maximum location of this distribution to larger number of scattering acts for the wavelengths of 400 and 500 nm being the latter the most pronounced. The increase of undergone scattering acts leads to the elongation of photon trajectories within the medium and results in the increase of the diffuse reflected light and the transmittance decrease.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2006
Subtitle of host publicationOptical Technologies in Biophysics and Medicine VIII
EditorsValery V. Tuchin
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Print)978-0-8194-6657-0
Publication statusPublished - 5 Nov 2007
MoE publication typeA4 Article in a conference publication
EventSaratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII - Saratov, Russian Federation
Duration: 26 Sep 200629 Sep 2006

Publication series

SeriesProgress in Biomedical Optics and Imaging
SeriesProceedings of SPIE


ConferenceSaratov Fall Meeting 2006
Country/TerritoryRussian Federation


  • Monte Carlo method
  • Nanoparticles
  • Number of scattering acts
  • Numerical simulation
  • Propagation of optical radiation
  • Stratum corneum
  • Titanium dioxide


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