Abstract
Mechanical pressure superficially applied on the human skin surface by a fiber-optic probe influences the spatial distribution of blood within the cutaneous tissues. Upon gradual load of weight on the probe, a stepwise increase in the skin reflectance spectra is observed. The decrease in the load follows the similar inverse staircase-like tendency. The observed stepwise reflectance spectra changes are due to, respectively, sequential extrusion of blood from the topical cutaneous vascular beds and their filling afterward. The obtained results are confirmed by Monte Carlo modeling. This implies that pressure-induced influence during the human skin diffuse reflectance spectra measurements in vivo should be taken into consideration, in particular, in the rapidly developing area of wearable gadgets for real-time monitoring of various human body parameters.
Original language | English |
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Article number | 110504 |
Journal | Journal of Biomedical Optics |
Volume | 22 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2017 |
MoE publication type | A1 Journal article-refereed |
Funding
The authors are grateful to Dr. Matti Huiku (General Electric Healthcare) for fruitful discussion and valuable comments at the initial stage of the letter preparation. The Academy of Finland (grants 260321 and 290596), the Russian Science Foundation (project 15-14-10008), MEPhI Academic Excellence Project (Contract No. 02.a03.21.0005), and the Government of Russian Federation (Grant No. 074-U01) are acknowledged for financial support.
Keywords
- cutaneous vascular beds
- diffuse reflectance spectra
- human skin
- probe pressure