Influence of whey-based fruit juice containing Lactobacillus rhamnosus on intestinal well-being and humoral immune response in healthy adults

Tarja Suomalainen (Corresponding Author), Hanna Lagström, Jaana Mättö, Maria Saarela, Heikki Arvilommi, Iina Laitinen, Arthur C. Ouwehand, Seppo Salminen

Research output: Contribution to journalArticleScientificpeer-review

11 Citations (Scopus)

Abstract

The ability of probiotics to balance intestinal microbes and to modulate gut immune system has been reported for several probiotic strains. In the present study, Lactobacillus rhamnosus strain VTT E-97800 (E800) or L. rhamnosus Lc705 (the latter in combination with Propionibacterium freudenreichii ssp. shermanii JS) were separately administered to healthy adult volunteers ( in both study groups) in a whey-based fruit juice. Survival of the potentially probiotic L. rhamnosus strains in the GI-tract and their effect on intestinal well-being and peripheral immune parameters were assessed. Both L. rhamnosus strains were recovered in high numbers in faecal samples during the consumption period and with few exceptions they were not detected after the 2 weeks follow-up period. Consumption of the juice supplemented with either of the L. rhamnosus strains did not have significant effect on faecal consistency or defecation frequency. No changes were observed in the immunological parameters (number or immunoglobulin A-, G- and M-secreting cells, expression of Fcα-receptor or complement receptors 1 and 3), except for a slight decrease in the number of IgA secreting cells during ingestion of the juice supplemented with L. rhamnosus Lc705 and P. freudenreichii ssp. shermanii JS. The results indicate that L. rhamnosus strains E800 and Lc705 had good survival ability in the GI-tract when administered in a whey-based fruit juice matrix. No adverse effects on intestinal function or on studied immunological parameters were observed during consumption of the whey based juice drink supplemented with the potential probiotic strains.
Original languageEnglish
Pages (from-to)788-795
Number of pages8
JournalLWT - Food Science and Technology
Volume39
Issue number7
DOIs
Publication statusPublished - 2006
MoE publication typeA1 Journal article-refereed

Fingerprint

Lactobacillus rhamnosus
fruit juices
Humoral Immunity
whey
humoral immunity
Probiotics
probiotics
Propionibacterium freudenreichii
juices
Immunoglobulin A
gastrointestinal system
Gastrointestinal Tract
Complement C1
Complement Receptors
immunoglobulin A
receptors
Complement C3
Defecation
defecation
Fc Receptors

Keywords

  • Probiotics
  • Immune regulation
  • Gut microbiota
  • Nutrition

Cite this

Suomalainen, Tarja ; Lagström, Hanna ; Mättö, Jaana ; Saarela, Maria ; Arvilommi, Heikki ; Laitinen, Iina ; Ouwehand, Arthur C. ; Salminen, Seppo. / Influence of whey-based fruit juice containing Lactobacillus rhamnosus on intestinal well-being and humoral immune response in healthy adults. In: LWT - Food Science and Technology. 2006 ; Vol. 39, No. 7. pp. 788-795.
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title = "Influence of whey-based fruit juice containing Lactobacillus rhamnosus on intestinal well-being and humoral immune response in healthy adults",
abstract = "The ability of probiotics to balance intestinal microbes and to modulate gut immune system has been reported for several probiotic strains. In the present study, Lactobacillus rhamnosus strain VTT E-97800 (E800) or L. rhamnosus Lc705 (the latter in combination with Propionibacterium freudenreichii ssp. shermanii JS) were separately administered to healthy adult volunteers ( in both study groups) in a whey-based fruit juice. Survival of the potentially probiotic L. rhamnosus strains in the GI-tract and their effect on intestinal well-being and peripheral immune parameters were assessed. Both L. rhamnosus strains were recovered in high numbers in faecal samples during the consumption period and with few exceptions they were not detected after the 2 weeks follow-up period. Consumption of the juice supplemented with either of the L. rhamnosus strains did not have significant effect on faecal consistency or defecation frequency. No changes were observed in the immunological parameters (number or immunoglobulin A-, G- and M-secreting cells, expression of Fcα-receptor or complement receptors 1 and 3), except for a slight decrease in the number of IgA secreting cells during ingestion of the juice supplemented with L. rhamnosus Lc705 and P. freudenreichii ssp. shermanii JS. The results indicate that L. rhamnosus strains E800 and Lc705 had good survival ability in the GI-tract when administered in a whey-based fruit juice matrix. No adverse effects on intestinal function or on studied immunological parameters were observed during consumption of the whey based juice drink supplemented with the potential probiotic strains.",
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Influence of whey-based fruit juice containing Lactobacillus rhamnosus on intestinal well-being and humoral immune response in healthy adults. / Suomalainen, Tarja (Corresponding Author); Lagström, Hanna; Mättö, Jaana; Saarela, Maria; Arvilommi, Heikki; Laitinen, Iina; Ouwehand, Arthur C.; Salminen, Seppo.

In: LWT - Food Science and Technology, Vol. 39, No. 7, 2006, p. 788-795.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Influence of whey-based fruit juice containing Lactobacillus rhamnosus on intestinal well-being and humoral immune response in healthy adults

AU - Suomalainen, Tarja

AU - Lagström, Hanna

AU - Mättö, Jaana

AU - Saarela, Maria

AU - Arvilommi, Heikki

AU - Laitinen, Iina

AU - Ouwehand, Arthur C.

AU - Salminen, Seppo

PY - 2006

Y1 - 2006

N2 - The ability of probiotics to balance intestinal microbes and to modulate gut immune system has been reported for several probiotic strains. In the present study, Lactobacillus rhamnosus strain VTT E-97800 (E800) or L. rhamnosus Lc705 (the latter in combination with Propionibacterium freudenreichii ssp. shermanii JS) were separately administered to healthy adult volunteers ( in both study groups) in a whey-based fruit juice. Survival of the potentially probiotic L. rhamnosus strains in the GI-tract and their effect on intestinal well-being and peripheral immune parameters were assessed. Both L. rhamnosus strains were recovered in high numbers in faecal samples during the consumption period and with few exceptions they were not detected after the 2 weeks follow-up period. Consumption of the juice supplemented with either of the L. rhamnosus strains did not have significant effect on faecal consistency or defecation frequency. No changes were observed in the immunological parameters (number or immunoglobulin A-, G- and M-secreting cells, expression of Fcα-receptor or complement receptors 1 and 3), except for a slight decrease in the number of IgA secreting cells during ingestion of the juice supplemented with L. rhamnosus Lc705 and P. freudenreichii ssp. shermanii JS. The results indicate that L. rhamnosus strains E800 and Lc705 had good survival ability in the GI-tract when administered in a whey-based fruit juice matrix. No adverse effects on intestinal function or on studied immunological parameters were observed during consumption of the whey based juice drink supplemented with the potential probiotic strains.

AB - The ability of probiotics to balance intestinal microbes and to modulate gut immune system has been reported for several probiotic strains. In the present study, Lactobacillus rhamnosus strain VTT E-97800 (E800) or L. rhamnosus Lc705 (the latter in combination with Propionibacterium freudenreichii ssp. shermanii JS) were separately administered to healthy adult volunteers ( in both study groups) in a whey-based fruit juice. Survival of the potentially probiotic L. rhamnosus strains in the GI-tract and their effect on intestinal well-being and peripheral immune parameters were assessed. Both L. rhamnosus strains were recovered in high numbers in faecal samples during the consumption period and with few exceptions they were not detected after the 2 weeks follow-up period. Consumption of the juice supplemented with either of the L. rhamnosus strains did not have significant effect on faecal consistency or defecation frequency. No changes were observed in the immunological parameters (number or immunoglobulin A-, G- and M-secreting cells, expression of Fcα-receptor or complement receptors 1 and 3), except for a slight decrease in the number of IgA secreting cells during ingestion of the juice supplemented with L. rhamnosus Lc705 and P. freudenreichii ssp. shermanii JS. The results indicate that L. rhamnosus strains E800 and Lc705 had good survival ability in the GI-tract when administered in a whey-based fruit juice matrix. No adverse effects on intestinal function or on studied immunological parameters were observed during consumption of the whey based juice drink supplemented with the potential probiotic strains.

KW - Probiotics

KW - Immune regulation

KW - Gut microbiota

KW - Nutrition

U2 - 10.1016/j.lwt.2005.05.012

DO - 10.1016/j.lwt.2005.05.012

M3 - Article

VL - 39

SP - 788

EP - 795

JO - LWT - Food Science and Technology

JF - LWT - Food Science and Technology

SN - 0023-6438

IS - 7

ER -