Informatics and computational strategies for the study of lipids

Laxman Yetukuri, Kim Ekroos, Antonio Vidal-Puig, Matej Orešič (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

135 Citations (Scopus)

Abstract

Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.
Original languageEnglish
Pages (from-to)121-127
JournalMolecular bioSystems
Volume4
Issue number2
DOIs
Publication statusPublished - 2008
MoE publication typeA1 Journal article-refereed

Keywords

  • lipidomics
  • lipids
  • informatics
  • bioinformatics
  • pathway analysis

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    Yetukuri, L., Ekroos, K., Vidal-Puig, A., & Orešič, M. (2008). Informatics and computational strategies for the study of lipids. Molecular bioSystems, 4(2), 121-127. https://doi.org/10.1039/b715468b