It was found that Oscillatoria agardhii strain 27 produced compounds toxic against mosquito larvae (Aedes albopictus), therefore, these compounds were extracted and separated for insecticide development. Structural characterization of the toxic fraction by 1H‐NMR and GC‐MS showed that these compounds are not the neurotoxins or hepatotoxins conventionally produced by Oscillatoria, but it contained a mixture of unsaturated fatty acids, oleic, linoleic, and γ‐linolenic acids, as well as saturated fatty acids, myristic, palmitic, and stearic acids. In a bioassay developed for these hydrophobic compounds using mosquito larvae, authentic unsaturated fatty acids were shown to be toxic, whereas saturated ones were not active. The results suggested that it might be possible to use unsaturated fatty acids as environmentally safe and effective insecticides without the side effects of the chemically synthesized insecticides.
|Publication status||Published - 2000|
|MoE publication type||A1 Journal article-refereed|