Insecticidal compounds against mosquito larvae from Oscillatoria agardhii strain 27

Ken-Ichi Harada (Corresponding Author), Mette Suomalainen, Hideaki Uchida, Hiroaki Masui, Kuniyo Ohmura, Jari Kiviranta, Marja-Leena Niku-Paavola, Takaya Ikemoto

Research output: Contribution to journalArticleScientificpeer-review

39 Citations (Scopus)


It was found that Oscillatoria agardhii strain 27 produced compounds toxic against mosquito larvae (Aedes albopictus), therefore, these compounds were extracted and separated for insecticide development. Structural characterization of the toxic fraction by 1H‐NMR and GC‐MS showed that these compounds are not the neurotoxins or hepatotoxins conventionally produced by Oscillatoria, but it contained a mixture of unsaturated fatty acids, oleic, linoleic, and γ‐linolenic acids, as well as saturated fatty acids, myristic, palmitic, and stearic acids. In a bioassay developed for these hydrophobic compounds using mosquito larvae, authentic unsaturated fatty acids were shown to be toxic, whereas saturated ones were not active. The results suggested that it might be possible to use unsaturated fatty acids as environmentally safe and effective insecticides without the side effects of the chemically synthesized insecticides.

Original languageEnglish
Pages (from-to)114-119
JournalEnvironmental Toxicology
Issue number2
Publication statusPublished - 2000
MoE publication typeA1 Journal article-refereed


Dive into the research topics of 'Insecticidal compounds against mosquito larvae from Oscillatoria agardhii strain 27'. Together they form a unique fingerprint.

Cite this