Integrated breast cancer genomics

Henrik Edgren, Olli Kallioniemi (Corresponding Author)

Research output: Contribution to journalReview ArticleScientificpeer-review

4 Citations (Scopus)

Abstract

Predicting survival and therapy responses of breast cancer patients is a significant challenge. Two studies in this issue of Cancer Cell present a novel integrated analysis of genomic and transcriptomic profiles of 145 primary breast cancers and 51 established cell lines. Data from clinical tumors highlighted mechanisms of disease and facilitated identification of potential therapeutic targets and prognostic biomarkers. An extensive well-characterized cancer cell line resource opens up opportunities to explore the determinants of cellular responses to existing and emerging therapies. Taken together, these studies illustrate how integrated molecular profiling may one day significantly impact diagnosis and therapeutic choice in human breast cancer.
Original languageEnglish
Pages (from-to)453-454
Number of pages2
JournalCancer Cell
Volume10
Issue number6
DOIs
Publication statusPublished - 2006
MoE publication typeA2 Review article in a scientific journal

Fingerprint

Genomics
Breast Neoplasms
Cell Line
Neoplasms
Therapeutics
Biomarkers
Survival

Keywords

  • cell lines
  • breast cancer
  • breast cancer risk
  • cellular response
  • therapeutic response
  • therapies

Cite this

Edgren, H., & Kallioniemi, O. (2006). Integrated breast cancer genomics. Cancer Cell, 10(6), 453-454. https://doi.org/10.1016/j.ccr.2006.11.007
Edgren, Henrik ; Kallioniemi, Olli. / Integrated breast cancer genomics. In: Cancer Cell. 2006 ; Vol. 10, No. 6. pp. 453-454.
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Edgren, H & Kallioniemi, O 2006, 'Integrated breast cancer genomics', Cancer Cell, vol. 10, no. 6, pp. 453-454. https://doi.org/10.1016/j.ccr.2006.11.007

Integrated breast cancer genomics. / Edgren, Henrik; Kallioniemi, Olli (Corresponding Author).

In: Cancer Cell, Vol. 10, No. 6, 2006, p. 453-454.

Research output: Contribution to journalReview ArticleScientificpeer-review

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AU - Edgren, Henrik

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KW - breast cancer risk

KW - cellular response

KW - therapeutic response

KW - therapies

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