We present a novel microfluidic chip that combines liquid chromatography (LC) column and heated nebulizer on a single chip. The heated nebulizer enables ionization using either atmospheric pressure chemical ionization (APCI) or atmospheric pressure photoionization (APPI) prior to detection by mass spectrometry (MS). The integrated chip is based on our previously presented separate LC and heated nebulizer chips.
|Publication status||Published - 2009|
|MoE publication type||Not Eligible|
|Event||35th International Conference on Micro & Nano Engineering, MNE 2009 - Ghent, Belgium|
Duration: 28 Sep 2009 → 1 Oct 2009
|Conference||35th International Conference on Micro & Nano Engineering, MNE 2009|
|Period||28/09/09 → 1/10/09|
- liquid chromatography
- mass spectrometry
Saarela, V., Haapala, M., Pól, J., Kolari, K., Kotiaho, T., Kostiainen, R., & Franssila, S. (2009). Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry. Paper presented at 35th International Conference on Micro & Nano Engineering, MNE 2009, Ghent, Belgium.