Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry

Ville Saarela, Markus Haapala, Jaroslav Pól, Kai Kolari, Tapio Kotiaho, Risto Kostiainen, Sami Franssila

Research output: Contribution to conferenceConference articleScientificpeer-review

Abstract

We present a novel microfluidic chip that combines liquid chromatography (LC) column and heated nebulizer on a single chip. The heated nebulizer enables ionization using either atmospheric pressure chemical ionization (APCI) or atmospheric pressure photoionization (APPI) prior to detection by mass spectrometry (MS). The integrated chip is based on our previously presented separate LC and heated nebulizer chips.
Original languageEnglish
Publication statusPublished - 2009
MoE publication typeNot Eligible
Event35th International Conference on Micro & Nano Engineering, MNE 2009 - Ghent, Belgium
Duration: 28 Sep 20091 Oct 2009

Conference

Conference35th International Conference on Micro & Nano Engineering, MNE 2009
CountryBelgium
CityGhent
Period28/09/091/10/09

Fingerprint

Liquid chromatography
Atmospheric pressure
Ionization
Mass spectrometry
Photoionization
Microfluidics

Keywords

  • silicon
  • microfluidics
  • liquid chromatography
  • mass spectrometry

Cite this

Saarela, V., Haapala, M., Pól, J., Kolari, K., Kotiaho, T., Kostiainen, R., & Franssila, S. (2009). Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry. Paper presented at 35th International Conference on Micro & Nano Engineering, MNE 2009, Ghent, Belgium.
Saarela, Ville ; Haapala, Markus ; Pól, Jaroslav ; Kolari, Kai ; Kotiaho, Tapio ; Kostiainen, Risto ; Franssila, Sami. / Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry. Paper presented at 35th International Conference on Micro & Nano Engineering, MNE 2009, Ghent, Belgium.
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title = "Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry",
abstract = "We present a novel microfluidic chip that combines liquid chromatography (LC) column and heated nebulizer on a single chip. The heated nebulizer enables ionization using either atmospheric pressure chemical ionization (APCI) or atmospheric pressure photoionization (APPI) prior to detection by mass spectrometry (MS). The integrated chip is based on our previously presented separate LC and heated nebulizer chips.",
keywords = "silicon, microfluidics, liquid chromatography, mass spectrometry",
author = "Ville Saarela and Markus Haapala and Jaroslav P{\'o}l and Kai Kolari and Tapio Kotiaho and Risto Kostiainen and Sami Franssila",
year = "2009",
language = "English",
note = "35th International Conference on Micro & Nano Engineering, MNE 2009 ; Conference date: 28-09-2009 Through 01-10-2009",

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Saarela, V, Haapala, M, Pól, J, Kolari, K, Kotiaho, T, Kostiainen, R & Franssila, S 2009, 'Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry' Paper presented at 35th International Conference on Micro & Nano Engineering, MNE 2009, Ghent, Belgium, 28/09/09 - 1/10/09, .

Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry. / Saarela, Ville; Haapala, Markus; Pól, Jaroslav; Kolari, Kai; Kotiaho, Tapio; Kostiainen, Risto; Franssila, Sami.

2009. Paper presented at 35th International Conference on Micro & Nano Engineering, MNE 2009, Ghent, Belgium.

Research output: Contribution to conferenceConference articleScientificpeer-review

TY - CONF

T1 - Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry

AU - Saarela, Ville

AU - Haapala, Markus

AU - Pól, Jaroslav

AU - Kolari, Kai

AU - Kotiaho, Tapio

AU - Kostiainen, Risto

AU - Franssila, Sami

PY - 2009

Y1 - 2009

N2 - We present a novel microfluidic chip that combines liquid chromatography (LC) column and heated nebulizer on a single chip. The heated nebulizer enables ionization using either atmospheric pressure chemical ionization (APCI) or atmospheric pressure photoionization (APPI) prior to detection by mass spectrometry (MS). The integrated chip is based on our previously presented separate LC and heated nebulizer chips.

AB - We present a novel microfluidic chip that combines liquid chromatography (LC) column and heated nebulizer on a single chip. The heated nebulizer enables ionization using either atmospheric pressure chemical ionization (APCI) or atmospheric pressure photoionization (APPI) prior to detection by mass spectrometry (MS). The integrated chip is based on our previously presented separate LC and heated nebulizer chips.

KW - silicon

KW - microfluidics

KW - liquid chromatography

KW - mass spectrometry

M3 - Conference article

ER -

Saarela V, Haapala M, Pól J, Kolari K, Kotiaho T, Kostiainen R et al. Integrated chip for liquid chromatography separation and atmospheric pressure ionization for mass spectrometry. 2009. Paper presented at 35th International Conference on Micro & Nano Engineering, MNE 2009, Ghent, Belgium.