Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation

Matej Orešič; Juha Koikkalainen; Erno Lindfors; Jussi Mattila; Tiina Heliö; Jyrki Lötjönen

Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation

Matej Orešič, Juha Koikkalainen, Erno Lindfors, Jussi Mattila, Tiina Heliö, Jyrki Lötjönen

VTT Technical Research Centre of Finland

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Professional

Abstract

In today's world, we are surrounded by systems that generate vast amounts of data. Consequently, there is an increasing gap between the data generated and the actual usable information extracted from it. We provide new software solutions to address this problem, focusing on the integration of biological and medical data. We developed a megNetr software platform that affords the fusing of heterogeneous lifescience and medical data and their visualisation. We demonstrate the software platform utility by integrating imaging and metabolomics data in a case study of patients carrying the Lamin A/C mutation which causes dilated cardiomyopathy.

Original language	English
Title of host publication	VTT Symposium on Service Science, Technology and Business
Editors	Pentti Vähä, Iiro Salkari, Petteri Alahuhta, Pekka Leviäkangas
Place of Publication	Espoo
Publisher	VTT Technical Research Centre of Finland
Pages	198-207
ISBN (Electronic)	978-951-38-6330-2
ISBN (Print)	978-951-38-6329-6
Publication status	Published - 2008
MoE publication type	D3 Professional conference proceedings
Event	VTT Symposium on Service Science, Technology and Business - Espoo, Finland Duration: 19 Aug 2008 → 19 Aug 2008

Publication series

Series	VTT Symposium
Number	253
ISSN	0357-9387

Conference

Conference	VTT Symposium on Service Science, Technology and Business
Country/Territory	Finland
City	Espoo
Period	19/08/08 → 19/08/08

Access to Document

https://publications.vtt.fi/pdf/symposiums/2008/S253.pdf

1 Report

VTT Symposium on Service Science, Technology and Business
Vähä, P. (Editor), Salkari, I. (Editor), Alahuhta, P. (Editor) & Leviäkangas, P. (Editor), 2008, Espoo: VTT Technical Research Centre of Finland. 210 p. (VTT Symposium; No. 253).
Research output: Book/Report › Report

Open Access

Cite this

Orešič, M., Koikkalainen, J., Lindfors, E., Mattila, J., Heliö, T., & Lötjönen, J. (2008). Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation. In P. Vähä, I. Salkari, P. Alahuhta, & P. Leviäkangas (Eds.), VTT Symposium on Service Science, Technology and Business (pp. 198-207). VTT Technical Research Centre of Finland. https://publications.vtt.fi/pdf/symposiums/2008/S253.pdf

Orešič, Matej ; Koikkalainen, Juha ; Lindfors, Erno et al. / Integration and visualisation of highly complex biological and medical data : Application to Lamin A/C mutation. VTT Symposium on Service Science, Technology and Business. editor / Pentti Vähä ; Iiro Salkari ; Petteri Alahuhta ; Pekka Leviäkangas. Espoo : VTT Technical Research Centre of Finland, 2008. pp. 198-207 (VTT Symposium; No. 253).

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abstract = "In today's world, we are surrounded by systems that generate vast amounts of data. Consequently, there is an increasing gap between the data generated and the actual usable information extracted from it. We provide new software solutions to address this problem, focusing on the integration of biological and medical data. We developed a megNetr software platform that affords the fusing of heterogeneous lifescience and medical data and their visualisation. We demonstrate the software platform utility by integrating imaging and metabolomics data in a case study of patients carrying the Lamin A/C mutation which causes dilated cardiomyopathy.",

author = "Matej Ore{\v s}i{\v c} and Juha Koikkalainen and Erno Lindfors and Jussi Mattila and Tiina Heli{\"o} and Jyrki L{\"o}tj{\"o}nen",

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language = "English",

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series = "VTT Symposium",

publisher = "VTT Technical Research Centre of Finland",

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pages = "198--207",

editor = "Pentti V{\"a}h{\"a} and Iiro Salkari and Petteri Alahuhta and Pekka Levi{\"a}kangas",

booktitle = "VTT Symposium on Service Science, Technology and Business",

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Orešič, M, Koikkalainen, J, Lindfors, E, Mattila, J, Heliö, T & Lötjönen, J 2008, Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation. in P Vähä, I Salkari, P Alahuhta & P Leviäkangas (eds), VTT Symposium on Service Science, Technology and Business. VTT Technical Research Centre of Finland, Espoo, VTT Symposium, no. 253, pp. 198-207, VTT Symposium on Service Science, Technology and Business , Espoo, Finland, 19/08/08. <https://publications.vtt.fi/pdf/symposiums/2008/S253.pdf>

Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation. / Orešič, Matej; Koikkalainen, Juha; Lindfors, Erno et al.
VTT Symposium on Service Science, Technology and Business. ed. / Pentti Vähä; Iiro Salkari; Petteri Alahuhta; Pekka Leviäkangas. Espoo: VTT Technical Research Centre of Finland, 2008. p. 198-207 (VTT Symposium; No. 253).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Professional

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AU - Orešič, Matej

AU - Koikkalainen, Juha

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AU - Heliö, Tiina

AU - Lötjönen, Jyrki

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AB - In today's world, we are surrounded by systems that generate vast amounts of data. Consequently, there is an increasing gap between the data generated and the actual usable information extracted from it. We provide new software solutions to address this problem, focusing on the integration of biological and medical data. We developed a megNetr software platform that affords the fusing of heterogeneous lifescience and medical data and their visualisation. We demonstrate the software platform utility by integrating imaging and metabolomics data in a case study of patients carrying the Lamin A/C mutation which causes dilated cardiomyopathy.

M3 - Conference article in proceedings

SN - 978-951-38-6329-6

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BT - VTT Symposium on Service Science, Technology and Business

A2 - Vähä, Pentti

A2 - Salkari, Iiro

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PB - VTT Technical Research Centre of Finland

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Orešič M, Koikkalainen J, Lindfors E, Mattila J, Heliö T, Lötjönen J. Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation. In Vähä P, Salkari I, Alahuhta P, Leviäkangas P, editors, VTT Symposium on Service Science, Technology and Business. Espoo: VTT Technical Research Centre of Finland. 2008. p. 198-207. (VTT Symposium; No. 253).

Integration and visualisation of highly complex biological and medical data: Application to Lamin A/C mutation

Abstract

Publication series

Conference

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Research output

VTT Symposium on Service Science, Technology and Business

Cite this