Integrins and Mutant p53 on the Road to Metastasis

Galina Selivanova, Johanna Ivaska (Corresponding Author)

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Understanding how tumor cells invade tissues is key to developing drugs to block metastasis. In this issue, Muller et al. (2009) report that a mutant form of the tumor suppressor p53 in cancer cells boosts the endocytic recycling of the adhesion molecule integrin α5β1 and of epidermal growth factor receptor, promoting invasion and metastasis.
Original languageEnglish
Pages (from-to)1220-1222
JournalCell
Volume139
Issue number7
DOIs
Publication statusPublished - 2009
MoE publication typeA1 Journal article-refereed

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