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Ketogenic diet slows down mitochondrial myopathy progression in mice
Sofia Ahola-Erkkilä
, Christopher Carroll
, Katja Peltola-Mjösund
, Valtteri Tulkki
, Ismo Mattila
, Tuulikki Seppänen-Laakso
, Matej Orešič
, Henna Tyynismaa
, Anu Suomalainen
*
*
Corresponding author for this work
Helsinki University Hospital
University of Helsinki
VTT (former employee or external)
Research output
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Contribution to journal
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Article
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Scientific
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peer-review
168
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Keyphrases
Mitochondrial Myopathy
100%
Ketogenic Diet
100%
Lipidomics
60%
Mitochondrial DNA
40%
Aging
20%
Metabolic Changes
20%
Neurodegenerative Diseases
20%
Amino Acid Content
20%
Mitochondria
20%
Plasma Phospholipids
20%
Metabolomics
20%
Effective Treatment
20%
Metabolic
20%
Low Glucose
20%
Free Amino Acids
20%
High-fat Diet
20%
Disease Progression
20%
Transgenic
20%
Disease Model
20%
Fat Content
20%
Lipid Levels
20%
Cell Culture Study
20%
Metabolite Changes
20%
Mitochondrial Dysfunction
20%
Cytochrome c Oxidase
20%
Mitochondrial Respiratory Chain Deficiency
20%
Mitochondrial Biogenesis
20%
Multisystem Disease
20%
Respiratory Chain Deficiency
20%
Mitochondrial DNA mutation
20%
Neuromuscular Disease
20%
Liver Lipid
20%
Late-onset
20%
DNA Concentration
20%
Adult Age
20%
Muscle Fiber
20%
Late-onset Myopathy
20%
DNA Quality
20%
Progressive Disease
20%
Ketone Body Metabolism
20%
Microstructural Abnormalities
20%
Mitochondrium
20%
Biochemistry, Genetics and Molecular Biology
Lipidomics
100%
Mitochondrial Myopathy
100%
Mitochondrial DNA
100%
Electron Transport Chain
66%
Wild Type
33%
Ketogenesis
33%
Amino Acids
33%
Mitochondrial Disorder
33%
Transgenics
33%
Metabolomics
33%
Morphology
33%
Mitochondrion
33%
Lipid Liver Level
33%
Metabolite
33%
Cell Culture
33%
Mitochondrial Biogenesis
33%
Phospholipid Blood Level
33%
Cytochrome C Oxidase
33%
INIS
mice
100%
diet
100%
mitochondria
100%
slowdown
100%
diseases
33%
levels
25%
dna
25%
chains
16%
muscles
16%
tools
8%
fibers
8%
production
8%
lipids
8%
plasma
8%
patients
8%
glucose
8%
aging
8%
liver
8%
phospholipids
8%
metabolites
8%
cell cultures
8%
amino acids
8%
mutants
8%
adults
8%
cytochromes
8%
oxidases
8%
fats
8%
ketones
8%
Neuroscience
Muscle Disorder
100%
Ketogenic Diet
100%
Mitochondrial DNA
60%
Electron Transport Chain
40%
Phospholipid
20%
Mitochondrion
20%
Neurodegenerative Disorder
20%
Neuromuscular Disorder
20%
Ketone Bodies
20%
Amino Acid
20%
Cell Culture
20%
Mitochondrial Biogenesis
20%
Cytochrome C Oxidase
20%
Blood Plasma
20%