MAGIC polymer gel for dosimetric verification in boron neutron capture therapy

Jouni Uusi-Simola, Sami Heikkinen, Petri Kotiluoto, Tom Serén, Tiina Seppaälä, Iiro Auterinen, Sauli Savolainen

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    16 Citations (Scopus)

    Abstract

    Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools developed to date. We tested the normoxic polymer gel dosimeter known by the acronym MAGIC (methacrylic and ascorbic acid in gelatin initiated by copper) to evaluate its use in boron neutron capture therapy (BNCT) dosimetry. We irradiated a large cylindrical gel phantom (diameter: 10 cm; length: 20 cm) in the epithermal neutron beam of the Finnish BNCT facility at the FiR 1 nuclear reactor. Neutron irradiation was simulated with a Monte Carlo radiation transport code MCNP. To compare dose-response, gel samples from the same production batch were also irradiated with 6 MV photons from a medical linear accelerator. Irradiated gel phantoms then underwent magnetic resonance imaging to determine their R2 relaxation rate maps. The measured and normalized dose distribution in the epithermal neutron beam was compared with the dose distribution calculated by computer simulation. The results support the feasibility of using MAGIC gel in BNCT dosimetry.

    Original languageEnglish
    Pages (from-to)114-123
    Number of pages10
    JournalJournal of Applied Clinical Medical Physics
    Volume8
    Issue number2
    DOIs
    Publication statusPublished - 1 Jan 2007
    MoE publication typeA1 Journal article-refereed

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    Keywords

    • BNCT
    • Gel dosimeter
    • MCNP
    • Neutron dosimetry

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