Mechanical characterisation and modelling of electrospun materials for biomedical applications

Katarzyna Polak-Krasna, Anthimos Georgiadis, Pirjo Heikkila

    Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

    3 Citations (Scopus)

    Abstract

    Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.
    Original languageEnglish
    Title of host publicationMedical Measurements and Applications (MeMeA), 2015 IEEE International Symposium on
    PublisherIEEE Institute of Electrical and Electronic Engineers
    Pages507 - 511
    ISBN (Electronic)978-1-4799-6477-2
    DOIs
    Publication statusPublished - 2 Jul 2015
    MoE publication typeA4 Article in a conference publication
    Event2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Torino, Italy
    Duration: 7 May 20159 May 2015

    Conference

    Conference2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015
    Abbreviated titleMeMeA 2015
    CountryItaly
    CityTorino
    Period7/05/159/05/15

    Keywords

    • electrospinning
    • FEM
    • modelling
    • nonwoven
    • tensile testing

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