Medication incompliance and vital signs in heart failure patients

I.G. Chouvarda, T. Mabote, A. Torabi, J. Caffarel, Mark van Gils, J. Cleland, N. Maglaveras

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

Abstract

The success of medication treatment is a crucial part of chronic cardiac patients' therapy. Health professionals are requested to dynamically optimize this procedure (medication initiation, titration, change of medication plans) for each patient. Assessment of the person's response to treatment, and assessment of adherence to treatment are essential in supporting these medical decisions. In this work, methods that apply biosignal analysis on vital signs data are presented, aiming to detect differences due to medication incompliance. These data, although gathered in controlled conditions, encompass physiological fluctuations introduced by different factors of daily life, such as medication timing and activity. Heart Failure data are normalized to personal levels, and classification models trained with a pair of features (SBP and HR in semirecumbent position) succeed in achieving accuracy over 97% in a crossvalidation setup, in detecting 48 hrs incompliance. Additionally, the differences in incompliance patterns between heart failure and hypertensive subjects are discussed. These results constitute a promising step towards application of vital signs measurement and analysis in homecare for incompliance detection.
Original languageEnglish
Title of host publicationThe International Conference on Health Informatics
Subtitle of host publicationICHI 2013
EditorsYT. Zhang
PublisherSpringer
Pages51-54
ISBN (Electronic)978-3-319-03005-0
ISBN (Print)978-3-319-03004-3
DOIs
Publication statusPublished - 2013
MoE publication typeNot Eligible
EventICHI 2013 - Vilamoura, Portugal
Duration: 7 Nov 20139 Nov 2013

Publication series

SeriesIFMBE Proceedings
Volume42
ISSN1680-0737

Conference

ConferenceICHI 2013
CountryPortugal
CityVilamoura
Period7/11/139/11/13

Fingerprint

Vital Signs
Heart Failure
Therapeutics
Health

Keywords

  • telemonitoring data
  • patient medication compliance
  • personal health systems

Cite this

Chouvarda, I. G., Mabote, T., Torabi, A., Caffarel, J., van Gils, M., Cleland, J., & Maglaveras, N. (2013). Medication incompliance and vital signs in heart failure patients. In YT. Zhang (Ed.), The International Conference on Health Informatics : ICHI 2013 (pp. 51-54). Springer. IFMBE Proceedings, Vol.. 42 https://doi.org/10.1007/978-3-319-03005-0_14
Chouvarda, I.G. ; Mabote, T. ; Torabi, A. ; Caffarel, J. ; van Gils, Mark ; Cleland, J. ; Maglaveras, N. / Medication incompliance and vital signs in heart failure patients. The International Conference on Health Informatics : ICHI 2013. editor / YT. Zhang. Springer, 2013. pp. 51-54 (IFMBE Proceedings, Vol. 42).
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title = "Medication incompliance and vital signs in heart failure patients",
abstract = "The success of medication treatment is a crucial part of chronic cardiac patients' therapy. Health professionals are requested to dynamically optimize this procedure (medication initiation, titration, change of medication plans) for each patient. Assessment of the person's response to treatment, and assessment of adherence to treatment are essential in supporting these medical decisions. In this work, methods that apply biosignal analysis on vital signs data are presented, aiming to detect differences due to medication incompliance. These data, although gathered in controlled conditions, encompass physiological fluctuations introduced by different factors of daily life, such as medication timing and activity. Heart Failure data are normalized to personal levels, and classification models trained with a pair of features (SBP and HR in semirecumbent position) succeed in achieving accuracy over 97{\%} in a crossvalidation setup, in detecting 48 hrs incompliance. Additionally, the differences in incompliance patterns between heart failure and hypertensive subjects are discussed. These results constitute a promising step towards application of vital signs measurement and analysis in homecare for incompliance detection.",
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Chouvarda, IG, Mabote, T, Torabi, A, Caffarel, J, van Gils, M, Cleland, J & Maglaveras, N 2013, Medication incompliance and vital signs in heart failure patients. in YT Zhang (ed.), The International Conference on Health Informatics : ICHI 2013. Springer, IFMBE Proceedings, vol. 42, pp. 51-54, ICHI 2013, Vilamoura, Portugal, 7/11/13. https://doi.org/10.1007/978-3-319-03005-0_14

Medication incompliance and vital signs in heart failure patients. / Chouvarda, I.G.; Mabote, T.; Torabi, A.; Caffarel, J.; van Gils, Mark; Cleland, J.; Maglaveras, N.

The International Conference on Health Informatics : ICHI 2013. ed. / YT. Zhang. Springer, 2013. p. 51-54 (IFMBE Proceedings, Vol. 42).

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

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Chouvarda IG, Mabote T, Torabi A, Caffarel J, van Gils M, Cleland J et al. Medication incompliance and vital signs in heart failure patients. In Zhang YT, editor, The International Conference on Health Informatics : ICHI 2013. Springer. 2013. p. 51-54. (IFMBE Proceedings, Vol. 42). https://doi.org/10.1007/978-3-319-03005-0_14