Sevoflurane is a volatile anesthetic which is reported to cause
epileptiform EEG changes together with undesired symptoms such as convulsions.
In this paper, an algorithm for the automatic detection of these EEG changes
is presented which could enable safer induction of anesthesia with sevoflurane
by informing the clinicians about the epileptiform EEG. EEG was recorded from
60 healthy female patients during sevoflurane anesthesia. A neurophysiologist
classified the EEG waveforms. Each anesthesia period lasted 6 minutes. 48
signal features were extracted from the raw EEG. 5-sec segments of EEG were
classified based on the extracted features using a decision tree with a
logistic regression based decisions and the classification results were
compared to the neurophysiologist's classifications. Awake EEG was recognized
with 69% / 96% (sensitivity / specificity), Burst suppression with 56% / 98%,
Epileptiform EEG with 83% / 87 %, normal slow anesthesia EEG with 86% / 64 %,
slow anesthesia EEG with monophasic pattern with 65% / 80 %, and slow
anesthesia EEG with monophasic pattern and spikes with 54% / 84%.
|Series||Annual International Conference of the IEEE Engineering in Medicine and Biology Society|