Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

Anna-Marja Aura, Tuulikki Seppänen-Laakso, Ismo Mattila, Sylvain Guyot, Catherine M. G. C. Renard, Jean-Marc Souquet, Veronique Cheynier, Kirsi-Marja Oksman-Caldentey

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientific


The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.
Original languageEnglish
Title of host publicationPolyphenols Communications 2006
PublisherUniversity of Manitoba
Number of pages2
Publication statusPublished - 2006
MoE publication typeB3 Non-refereed article in conference proceedings
EventXXIII International Conference on Polyphenols - Winnipeg, Canada
Duration: 22 Aug 200625 Sep 2006


ConferenceXXIII International Conference on Polyphenols


Cite this

Aura, A-M., Seppänen-Laakso, T., Mattila, I., Guyot, S., Renard, C. M. G. C., Souquet, J-M., Cheynier, V., & Oksman-Caldentey, K-M. (2006). Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. In Polyphenols Communications 2006 University of Manitoba.