Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

Anna-Marja Aura, Tuulikki Seppänen-Laakso, Ismo Mattila, Sylvain Guyot, Catherine M. G. C. Renard, Jean-Marc Souquet, Veronique Cheynier, Kirsi-Marja Oksman-Caldentey

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientific

Abstract

The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.
Original languageEnglish
Title of host publicationPolyphenols Communications 2006
PublisherUniversity of Manitoba
Number of pages2
Publication statusPublished - 2006
MoE publication typeB3 Non-refereed article in conference proceedings
EventXXIII International Conference on Polyphenols - Winnipeg, Canada
Duration: 22 Aug 200625 Sep 2006

Conference

ConferenceXXIII International Conference on Polyphenols
CountryCanada
CityWinnipeg
Period22/08/0625/09/06

Fingerprint

Proanthocyanidins
Catechin
Microbiota
Stereoisomerism
In Vitro Techniques

Cite this

Aura, A-M., Seppänen-Laakso, T., Mattila, I., Guyot, S., Renard, C. M. G. C., Souquet, J-M., ... Oksman-Caldentey, K-M. (2006). Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. In Polyphenols Communications 2006 University of Manitoba.
Aura, Anna-Marja ; Seppänen-Laakso, Tuulikki ; Mattila, Ismo ; Guyot, Sylvain ; Renard, Catherine M. G. C. ; Souquet, Jean-Marc ; Cheynier, Veronique ; Oksman-Caldentey, Kirsi-Marja. / Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. Polyphenols Communications 2006. University of Manitoba, 2006.
@inproceedings{166573c7451e4d35a33ca42201900c88,
title = "Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro",
abstract = "The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.",
author = "Anna-Marja Aura and Tuulikki Sepp{\"a}nen-Laakso and Ismo Mattila and Sylvain Guyot and Renard, {Catherine M. G. C.} and Jean-Marc Souquet and Veronique Cheynier and Kirsi-Marja Oksman-Caldentey",
year = "2006",
language = "English",
booktitle = "Polyphenols Communications 2006",
publisher = "University of Manitoba",
address = "Canada",

}

Aura, A-M, Seppänen-Laakso, T, Mattila, I, Guyot, S, Renard, CMGC, Souquet, J-M, Cheynier, V & Oksman-Caldentey, K-M 2006, Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. in Polyphenols Communications 2006. University of Manitoba, XXIII International Conference on Polyphenols, Winnipeg, Canada, 22/08/06.

Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. / Aura, Anna-Marja; Seppänen-Laakso, Tuulikki; Mattila, Ismo; Guyot, Sylvain; Renard, Catherine M. G. C.; Souquet, Jean-Marc; Cheynier, Veronique; Oksman-Caldentey, Kirsi-Marja.

Polyphenols Communications 2006. University of Manitoba, 2006.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientific

TY - GEN

T1 - Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

AU - Aura, Anna-Marja

AU - Seppänen-Laakso, Tuulikki

AU - Mattila, Ismo

AU - Guyot, Sylvain

AU - Renard, Catherine M. G. C.

AU - Souquet, Jean-Marc

AU - Cheynier, Veronique

AU - Oksman-Caldentey, Kirsi-Marja

PY - 2006

Y1 - 2006

N2 - The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.

AB - The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.

M3 - Conference article in proceedings

BT - Polyphenols Communications 2006

PB - University of Manitoba

ER -

Aura A-M, Seppänen-Laakso T, Mattila I, Guyot S, Renard CMGC, Souquet J-M et al. Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. In Polyphenols Communications 2006. University of Manitoba. 2006