Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

Anna-Marja Aura, Tuulikki Seppänen-Laakso, Ismo Mattila, Sylvain Guyot, Catherine M. G. C. Renard, Jean-Marc Souquet, Veronique Cheynier, Kirsi-Marja Oksman-Caldentey

    Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientific


    The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.
    Original languageEnglish
    Title of host publicationPolyphenols Communications 2006
    PublisherUniversity of Manitoba
    Number of pages2
    Publication statusPublished - 2006
    MoE publication typeB3 Non-refereed article in conference proceedings
    EventXXIII International Conference on Polyphenols - Winnipeg, Canada
    Duration: 22 Aug 200625 Sept 2006


    ConferenceXXIII International Conference on Polyphenols


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