Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

Anna-Marja Aura; Tuulikki Seppänen-Laakso; Ismo Mattila; Sylvain Guyot; Catherine M. G. C. Renard; Jean-Marc Souquet; Veronique Cheynier; Kirsi-Marja Oksman-Caldentey

Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

Anna-Marja Aura, Tuulikki Seppänen-Laakso, Ismo Mattila, Sylvain Guyot, Catherine M. G. C. Renard, Jean-Marc Souquet, Veronique Cheynier, Kirsi-Marja Oksman-Caldentey

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific

Abstract

The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.

Original language	English
Title of host publication	Polyphenols Communications 2006
Publisher	University of Manitoba
Number of pages	2
Publication status	Published - 2006
MoE publication type	B3 Non-refereed article in conference proceedings
Event	XXIII International Conference on Polyphenols - Winnipeg, Canada Duration: 22 Aug 2006 → 25 Sept 2006

Conference

Conference	XXIII International Conference on Polyphenols
Country/Territory	Canada
City	Winnipeg
Period	22/08/06 → 25/09/06

Cite this

@inproceedings{166573c7451e4d35a33ca42201900c88,

title = "Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro",

abstract = "The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.",

author = "Anna-Marja Aura and Tuulikki Sepp{\"a}nen-Laakso and Ismo Mattila and Sylvain Guyot and Renard, \{Catherine M. G. C.\} and Jean-Marc Souquet and Veronique Cheynier and Kirsi-Marja Oksman-Caldentey",

year = "2006",

language = "English",

booktitle = "Polyphenols Communications 2006",

publisher = "University of Manitoba",

address = "Canada",

note = "XXIII International Conference on Polyphenols ; Conference date: 22-08-2006 Through 25-09-2006",

}

Aura, A-M, Seppänen-Laakso, T, Mattila, I, Guyot, S, Renard, CMGC, Souquet, J-M, Cheynier, V & Oksman-Caldentey, K-M 2006, Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro. in Polyphenols Communications 2006. University of Manitoba, XXIII International Conference on Polyphenols, Winnipeg, Manitoba, Canada, 22/08/06.

TY - GEN

T1 - Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

AU - Aura, Anna-Marja

AU - Seppänen-Laakso, Tuulikki

AU - Mattila, Ismo

AU - Guyot, Sylvain

AU - Renard, Catherine M. G. C.

AU - Souquet, Jean-Marc

AU - Cheynier, Veronique

AU - Oksman-Caldentey, Kirsi-Marja

PY - 2006

Y1 - 2006

N2 - The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.

AB - The aim of the study was to investigate in vitro microbial metabolism of flavan-3-ols [(+)-catechin, (-)-epicatechin, proanthocyanidins (PA)] from different plant sources using human fecal microbiota as an inoculum to identify the main degradation products of flavan-3-ols. Microbial transformations varied depending on the source and structure of the flavan-3-ols with clear differences in time-extent profiles for each substrate. Whereas (+)-catechin gave rise to 3,4-dihydroxyphenylpropionic acid as a primary product, the stereoisomer (-)-epicatechin, surprisingly, did not.

M3 - Conference article in proceedings

BT - Polyphenols Communications 2006

PB - University of Manitoba

T2 - XXIII International Conference on Polyphenols

Y2 - 22 August 2006 through 25 September 2006

ER -

Microbial metabolism of (+)-catechin, (-)-epicatechin and proanthocyanidins by human fecal microbiota in vitro

Abstract

Conference

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