Microneedle based sampling for breast cancer tissues

Ari Hokkanen, Ingmar Stuns, P. Schmid, Annukka Kokkonen, A. Steinecker, J. Budczies, Päivi Heimala, Leena Hakalahti

    Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

    Abstract

    We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.
    Original languageEnglish
    Title of host publicationProcedings
    Subtitle of host publication 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
    Pages1154-1156
    Publication statusPublished - 2014
    MoE publication typeA4 Article in a conference publication
    Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
    Duration: 26 Oct 201430 Oct 2014
    Conference number: 18

    Conference

    Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
    Abbreviated titleMicroTAS 2014
    Country/TerritoryUnited States
    CitySan Antonio
    Period26/10/1430/10/14

    Keywords

    • cancer
    • microneedle
    • sampling
    • tissue

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