Microneedle based sampling for breast cancer tissues

Ari Hokkanen, Ingmar Stuns, P. Schmid, Annukka Kokkonen, A. Steinecker, J. Budczies, Päivi Heimala, Leena Hakalahti

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

Abstract

We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.
Original languageEnglish
Title of host publicationProcedings
Subtitle of host publication 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Pages1154-1156
Publication statusPublished - 2014
MoE publication typeA4 Article in a conference publication
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 26 Oct 201430 Oct 2014
Conference number: 18

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Abbreviated titleMicroTAS 2014
CountryUnited States
CitySan Antonio
Period26/10/1430/10/14

Fingerprint

Tissue
Sampling
Lipids
Micromanipulators
Silicon
Microfluidics
Needles
Mass spectrometry
Polymers
Microscopes
Decision making

Keywords

  • cancer
  • microneedle
  • sampling
  • tissue

Cite this

Hokkanen, A., Stuns, I., Schmid, P., Kokkonen, A., Steinecker, A., Budczies, J., ... Hakalahti, L. (2014). Microneedle based sampling for breast cancer tissues. In Procedings: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 1154-1156)
Hokkanen, Ari ; Stuns, Ingmar ; Schmid, P. ; Kokkonen, Annukka ; Steinecker, A. ; Budczies, J. ; Heimala, Päivi ; Hakalahti, Leena. / Microneedle based sampling for breast cancer tissues. Procedings: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 2014. pp. 1154-1156
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title = "Microneedle based sampling for breast cancer tissues",
abstract = "We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.",
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Hokkanen, A, Stuns, I, Schmid, P, Kokkonen, A, Steinecker, A, Budczies, J, Heimala, P & Hakalahti, L 2014, Microneedle based sampling for breast cancer tissues. in Procedings: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. pp. 1154-1156, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, United States, 26/10/14.

Microneedle based sampling for breast cancer tissues. / Hokkanen, Ari; Stuns, Ingmar; Schmid, P.; Kokkonen, Annukka; Steinecker, A.; Budczies, J.; Heimala, Päivi; Hakalahti, Leena.

Procedings: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 2014. p. 1154-1156.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

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T1 - Microneedle based sampling for breast cancer tissues

AU - Hokkanen, Ari

AU - Stuns, Ingmar

AU - Schmid, P.

AU - Kokkonen, Annukka

AU - Steinecker, A.

AU - Budczies, J.

AU - Heimala, Päivi

AU - Hakalahti, Leena

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N2 - We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.

AB - We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.

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KW - microneedle

KW - sampling

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Hokkanen A, Stuns I, Schmid P, Kokkonen A, Steinecker A, Budczies J et al. Microneedle based sampling for breast cancer tissues. In Procedings: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 2014. p. 1154-1156