Microneedle based sampling for breast cancer tissues

Ari Hokkanen; Ingmar Stuns; P. Schmid; Annukka Kokkonen; A. Steinecker; J. Budczies; Päivi Heimala; Leena Hakalahti

Microneedle based sampling for breast cancer tissues

Ari Hokkanen
, Ingmar Stuns
, P. Schmid
, Annukka Kokkonen
, A. Steinecker
, J. Budczies
, Päivi Heimala
, Leena Hakalahti

Centre Suisse d'Electronique et de Microtechnique S.A. (CSEM)
Charité Universitätsmedizin Berlin

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

Abstract

We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.

Original language	English
Title of host publication	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Pages	1154-1156
ISBN (Electronic)	978-0-9798064-7-6
Publication status	Published - 2014
MoE publication type	A4 Article in a conference publication
Event	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014 Conference number: 18

Conference

Conference	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Abbreviated title	MicroTAS 2014
Country/Territory	United States
City	San Antonio
Period	26/10/14 → 30/10/14

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cancer
microneedle
sampling
tissue

Access to Document

http://www.rsc.org/images/loc/2014/PDFs/Papers/381_0625.pdf

Cite this

@inproceedings{19d930809ada4c939566d33292ea9449,

title = "Microneedle based sampling for breast cancer tissues",

abstract = "We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.",

keywords = "cancer, microneedle, sampling, tissue",

author = "Ari Hokkanen and Ingmar Stuns and P. Schmid and Annukka Kokkonen and A. Steinecker and J. Budczies and P{\"a}ivi Heimala and Leena Hakalahti",

year = "2014",

language = "English",

isbn = "978-1-63439-697-4",

pages = "1154--1156",

booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",

note = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",

}

Hokkanen, A, Stuns, I, Schmid, P, Kokkonen, A, Steinecker, A, Budczies, J, Heimala, P & Hakalahti, L 2014, Microneedle based sampling for breast cancer tissues. in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. pp. 1154-1156, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, Texas, United States, 26/10/14. <http://www.rsc.org/images/loc/2014/PDFs/Papers/381_0625.pdf>

TY - GEN

T1 - Microneedle based sampling for breast cancer tissues

AU - Hokkanen, Ari

AU - Stuns, Ingmar

AU - Schmid, P.

AU - Kokkonen, Annukka

AU - Steinecker, A.

AU - Budczies, J.

AU - Heimala, Päivi

AU - Hakalahti, Leena

N1 - Conference code: 18

PY - 2014

Y1 - 2014

N2 - We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.

AB - We have developed a microneedle based sample collecting system that is capable of extracting lipid samples from an artificial lipid layer on a microscope slide. Such a system can be used in the future to collect lipid samples from real tissue sections and help surgeons in their decision making during surgical operations. The sample collection system consists of a silicon based multiport microneedle integrated with polymer microfluidics. A special micromanipulator system is developed to control the positioning of the needle and the sampling event. Mass spectrometry analysis is used to show that the lipid extraction from a standard lipid sample can be successfully done.

KW - cancer

KW - microneedle

KW - sampling

KW - tissue

M3 - Conference article in proceedings

SN - 978-1-63439-697-4

SP - 1154

EP - 1156

BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Y2 - 26 October 2014 through 30 October 2014

ER -

Microneedle based sampling for breast cancer tissues

Abstract

Conference

UN SDGs

Keywords

Access to Document

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Cite this