Abstract
| Original language | English |
|---|---|
| Title of host publication | Advanced Gibbs Energy Methods for Functional Materials and Processes |
| Subtitle of host publication | ChemSheet 1999-2009 |
| Place of Publication | Espoo |
| Publisher | VTT Technical Research Centre of Finland |
| Pages | 138-145 |
| ISBN (Electronic) | 978-951-38-7331-8 |
| ISBN (Print) | 978-951-38-7330-1 |
| Publication status | Published - 2009 |
| MoE publication type | Not Eligible |
Publication series
| Series | VTT Tiedotteita - Research Notes |
|---|---|
| Number | 2506 |
| ISSN | 1235-0605 |
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Modeling biochemical systems with constrained Gibbs energy minimization. / Blomberg, Peter.
Advanced Gibbs Energy Methods for Functional Materials and Processes: ChemSheet 1999-2009. Espoo : VTT Technical Research Centre of Finland, 2009. p. 138-145 (VTT Tiedotteita - Research Notes; No. 2506).Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional
TY - CHAP
T1 - Modeling biochemical systems with constrained Gibbs energy minimization
AU - Blomberg, Peter
N1 - Project code: 26639
PY - 2009
Y1 - 2009
N2 - Rising costs of fossil resources and products based thereupon has launched a large-scale interest in processing green biomass into raw materials for the chemical industry. Environmental awareness and concern for the global community spur researchers towards seeking thermally efficient and minimally wasteful processes. Current and future biorefinery concepts will use microorganisms to convert lignocellulosic feeds into valuable platform chemicals. However, very few natural organisms produce the desired intermediates in suitable amounts for industrial scale production. The biochemical systems in metabolic engineering are rich in different types of chemical species, modestly reactive, and contain many distinct compartments. A novel method based on multicomponent multiphase Gibbs energy minimization with kinetic constraints and pertinent Legendre transforms has been developed to support thermodynamic modeling of biochemical systems.
AB - Rising costs of fossil resources and products based thereupon has launched a large-scale interest in processing green biomass into raw materials for the chemical industry. Environmental awareness and concern for the global community spur researchers towards seeking thermally efficient and minimally wasteful processes. Current and future biorefinery concepts will use microorganisms to convert lignocellulosic feeds into valuable platform chemicals. However, very few natural organisms produce the desired intermediates in suitable amounts for industrial scale production. The biochemical systems in metabolic engineering are rich in different types of chemical species, modestly reactive, and contain many distinct compartments. A novel method based on multicomponent multiphase Gibbs energy minimization with kinetic constraints and pertinent Legendre transforms has been developed to support thermodynamic modeling of biochemical systems.
M3 - Chapter or book article
SN - 978-951-38-7330-1
T3 - VTT Tiedotteita - Research Notes
SP - 138
EP - 145
BT - Advanced Gibbs Energy Methods for Functional Materials and Processes
PB - VTT Technical Research Centre of Finland
CY - Espoo
ER -