Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry

Tiina Seppälä, Jyrki Vähätalo, Iiro Auterinen, Antti Kosunen, David Nigg, Floyd Wheeler, Sauli Savolainen (Corresponding Author)

    Research output: Contribution to journalArticleScientificpeer-review

    15 Citations (Scopus)

    Abstract

    The aim of this study was to define the most suitable brain tissue phantom material for neutron capture therapy (NCT). The calculated distributions of the thermal neutron fluence and the fast neutron and γ dose in normal brain tissue defined by ICRU were compared to those in four brain tissue substitutes: water, PMMA and two normal brain tissue substitute liquids, A and B, defined by us. Liquid B is an excellent material to simulate the neutron and γ interactions in normal brain tissue and it can be considered for use in situations for which higher accuracy is required, although it may not be suitable for routine use. Water is a suitable brain tissue substitute for periodic epithermal beam calibration, for routine quality control and for intercomparison of beams in NCT dosimetry.
    Original languageEnglish
    Pages (from-to)239-246
    Number of pages8
    JournalRadiation Physics and Chemistry
    Volume55
    Issue number3
    DOIs
    Publication statusPublished - 1999
    MoE publication typeA1 Journal article-refereed

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    dosimeters
    brain
    therapy
    substitutes
    neutrons
    fast neutrons
    liquids
    quality control
    thermal neutrons
    water
    fluence
    dosage
    interactions

    Cite this

    Seppälä, Tiina ; Vähätalo, Jyrki ; Auterinen, Iiro ; Kosunen, Antti ; Nigg, David ; Wheeler, Floyd ; Savolainen, Sauli. / Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry. In: Radiation Physics and Chemistry. 1999 ; Vol. 55, No. 3. pp. 239-246.
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    Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry. / Seppälä, Tiina; Vähätalo, Jyrki; Auterinen, Iiro; Kosunen, Antti; Nigg, David; Wheeler, Floyd; Savolainen, Sauli (Corresponding Author).

    In: Radiation Physics and Chemistry, Vol. 55, No. 3, 1999, p. 239-246.

    Research output: Contribution to journalArticleScientificpeer-review

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    T1 - Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry

    AU - Seppälä, Tiina

    AU - Vähätalo, Jyrki

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    AU - Nigg, David

    AU - Wheeler, Floyd

    AU - Savolainen, Sauli

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