Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry

Tiina Seppälä, Jyrki Vähätalo, Iiro Auterinen, Antti Kosunen, David Nigg, Floyd Wheeler, Sauli Savolainen (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

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Abstract

The aim of this study was to define the most suitable brain tissue phantom material for neutron capture therapy (NCT). The calculated distributions of the thermal neutron fluence and the fast neutron and γ dose in normal brain tissue defined by ICRU were compared to those in four brain tissue substitutes: water, PMMA and two normal brain tissue substitute liquids, A and B, defined by us. Liquid B is an excellent material to simulate the neutron and γ interactions in normal brain tissue and it can be considered for use in situations for which higher accuracy is required, although it may not be suitable for routine use. Water is a suitable brain tissue substitute for periodic epithermal beam calibration, for routine quality control and for intercomparison of beams in NCT dosimetry.
Original languageEnglish
Pages (from-to)239-246
Number of pages8
JournalRadiation Physics and Chemistry
Volume55
Issue number3
DOIs
Publication statusPublished - 1999
MoE publication typeA1 Journal article-refereed

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dosimeters
brain
therapy
substitutes
neutrons
fast neutrons
liquids
quality control
thermal neutrons
water
fluence
dosage
interactions

Cite this

Seppälä, Tiina ; Vähätalo, Jyrki ; Auterinen, Iiro ; Kosunen, Antti ; Nigg, David ; Wheeler, Floyd ; Savolainen, Sauli. / Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry. In: Radiation Physics and Chemistry. 1999 ; Vol. 55, No. 3. pp. 239-246.
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Modelling of brain tissue substitutes for phantom materials in neutron capture therapy (NCT) dosimetry. / Seppälä, Tiina; Vähätalo, Jyrki; Auterinen, Iiro; Kosunen, Antti; Nigg, David; Wheeler, Floyd; Savolainen, Sauli (Corresponding Author).

In: Radiation Physics and Chemistry, Vol. 55, No. 3, 1999, p. 239-246.

Research output: Contribution to journalArticleScientificpeer-review

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AU - Wheeler, Floyd

AU - Savolainen, Sauli

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