Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach

Anna-Marja Hoffren, Markku Saloheimo, Pam Thomas, John Overington, Mark Johnson, Tom Blundell

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review


White‐rot fungi degrade lignin more rapidly and extensively than other microbes studied. The breakdown of lignin by these fungi is mediated by ligninolytic enzymes including lignin peroxidases. The catalytic properties of a number of peroxidases have been extensively studied but the crystal structure of only the yeast cytochrome c peroxidase is known. Hydrophobic cluster analysis (HCA), a method for comparing proteins with low sequence homology, suggests that peroxidases are evolutionally related.
Original languageEnglish
Title of host publicationAdvances in biomolecular simulations
Place of PublicationObernai
Publication statusPublished - 1991
MoE publication typeA4 Article in a conference publication
EventInternational Symposium on Advances in Biomolecular Simulations - Obernai, France
Duration: 12 Mar 199114 Mar 1991

Publication series

SeriesAIP Conference Proceedings


ConferenceInternational Symposium on Advances in Biomolecular Simulations

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