Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach

Anna-Marja Hoffren; Markku Saloheimo; Pam Thomas; John Overington; Mark Johnson; Tom Blundell

doi:10.1063/1.41321

Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach

Anna-Marja Hoffren, Markku Saloheimo, Pam Thomas, John Overington, Mark Johnson, Tom Blundell

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

Abstract

White‐rot fungi degrade lignin more rapidly and extensively than other microbes studied. The breakdown of lignin by these fungi is mediated by ligninolytic enzymes including lignin peroxidases. The catalytic properties of a number of peroxidases have been extensively studied but the crystal structure of only the yeast cytochrome c peroxidase is known. Hydrophobic cluster analysis (HCA), a method for comparing proteins with low sequence homology, suggests that peroxidases are evolutionally related.

Original language	English
Title of host publication	Advances in biomolecular simulations
Place of Publication	Obernai
Pages	346-347
DOIs	https://doi.org/10.1063/1.41321
Publication status	Published - 1991
MoE publication type	A4 Article in a conference publication
Event	International Symposium on Advances in Biomolecular Simulations - Obernai, France Duration: 12 Mar 1991 → 14 Mar 1991

Publication series

Series	AIP Conference Proceedings
Volume	239
ISSN	0094-243X

Conference

Conference	International Symposium on Advances in Biomolecular Simulations
Country/Territory	France
City	Obernai
Period	12/03/91 → 14/03/91

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10.1063/1.41321

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title = "Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach",

abstract = "White‐rot fungi degrade lignin more rapidly and extensively than other microbes studied. The breakdown of lignin by these fungi is mediated by ligninolytic enzymes including lignin peroxidases. The catalytic properties of a number of peroxidases have been extensively studied but the crystal structure of only the yeast cytochrome c peroxidase is known. Hydrophobic cluster analysis (HCA), a method for comparing proteins with low sequence homology, suggests that peroxidases are evolutionally related.",

author = "Anna-Marja Hoffren and Markku Saloheimo and Pam Thomas and John Overington and Mark Johnson and Tom Blundell",

note = "Project code: BIO8015; International Symposium on Advances in Biomolecular Simulations ; Conference date: 12-03-1991 Through 14-03-1991",

year = "1991",

doi = "10.1063/1.41321",

language = "English",

series = "AIP Conference Proceedings",

publisher = "American Institute of Physics (AIP)",

pages = "346--347",

booktitle = "Advances in biomolecular simulations",

}

Hoffren, A-M, Saloheimo, M, Thomas, P, Overington, J, Johnson, M & Blundell, T 1991, Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach. in Advances in biomolecular simulations. Obernai, AIP Conference Proceedings, vol. 239, pp. 346-347, International Symposium on Advances in Biomolecular Simulations, Obernai, France, 12/03/91. https://doi.org/10.1063/1.41321

Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach. / Hoffren, Anna-Marja; Saloheimo, Markku; Thomas, Pam et al.
Advances in biomolecular simulations. Obernai, 1991. p. 346-347 (AIP Conference Proceedings, Vol. 239).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

TY - GEN

T1 - Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach

AU - Hoffren, Anna-Marja

AU - Saloheimo, Markku

AU - Thomas, Pam

AU - Overington, John

AU - Johnson, Mark

AU - Blundell, Tom

N1 - Project code: BIO8015

PY - 1991

Y1 - 1991

N2 - White‐rot fungi degrade lignin more rapidly and extensively than other microbes studied. The breakdown of lignin by these fungi is mediated by ligninolytic enzymes including lignin peroxidases. The catalytic properties of a number of peroxidases have been extensively studied but the crystal structure of only the yeast cytochrome c peroxidase is known. Hydrophobic cluster analysis (HCA), a method for comparing proteins with low sequence homology, suggests that peroxidases are evolutionally related.

AB - White‐rot fungi degrade lignin more rapidly and extensively than other microbes studied. The breakdown of lignin by these fungi is mediated by ligninolytic enzymes including lignin peroxidases. The catalytic properties of a number of peroxidases have been extensively studied but the crystal structure of only the yeast cytochrome c peroxidase is known. Hydrophobic cluster analysis (HCA), a method for comparing proteins with low sequence homology, suggests that peroxidases are evolutionally related.

U2 - 10.1063/1.41321

DO - 10.1063/1.41321

M3 - Conference article in proceedings

T3 - AIP Conference Proceedings

SP - 346

EP - 347

BT - Advances in biomolecular simulations

CY - Obernai

T2 - International Symposium on Advances in Biomolecular Simulations

Y2 - 12 March 1991 through 14 March 1991

ER -

Modelling the lignin peroxidase LIII of Phlebia radiata using a knowledge-based approach

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