Abstract
Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.
| Original language | English |
|---|---|
| Article number | 016003 |
| Journal | Journal of Biomedical Optics |
| Volume | 23 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2018 |
| MoE publication type | A1 Journal article-refereed |
Funding
The authors thank Dr. S. V. Eremina (Department of English and Intercultural Communication of Saratov State University) for proof of English, L.E. Dolotov for help in design of the registration part of the AR Atago DR-M2 1550 (Atago, Japan). This study was supported in part by Academy of Finland projects Grants 288164 (I.Yu.Y.), 260321 and 290596 (A.P.P., A.V.B.); the Russian Presidential Grant Nos. MK-6009.2016.2 (I.Yu.Y.) and NSh-7898.2016.2 (V.V.T. and I.Yu.Y.), the Government of Russian Federation Grant No. 074-U01 (A.P.P., A.V.B., I.V.M., and V.V.T.), and the Tomsk State University Competitiveness Improvement Programme (I.Yu.Y. and V.V.T.). I.V.M. also acknowledges a partial support provided by the Russian Science Foundation project No. 15-14-10008. All authors have no financial interest.
Keywords
- Abbe refractometry
- adipose tissue
- heating
- lipolysis
- optical coherence tomography
- phase transition
- refractive index