Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

Irina Y. Yanina; Alexey P. Popov; Alexander V. Bykov; Igor V. Meglinski; Valery V. Tuchin

doi:10.1117/1.JBO.23.1.016003

Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

Irina Y. Yanina, Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, Valery V. Tuchin

Not published at VTT

Research output: Contribution to journal › Article › Scientific › peer-review

4 Citations (Scopus)

Abstract

Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.

Original language	English
Article number	016003
Journal	Journal of Biomedical Optics
Volume	23
Issue number	1
DOIs	https://doi.org/10.1117/1.JBO.23.1.016003
Publication status	Published - Jan 2018
MoE publication type	A1 Journal article-refereed

Keywords

Abbe refractometry
adipose tissue
heating
lipolysis
optical coherence tomography
phase transition
refractive index

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10.1117/1.JBO.23.1.016003

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title = "Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry",

abstract = "Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.",

keywords = "Abbe refractometry, adipose tissue, heating, lipolysis, optical coherence tomography, phase transition, refractive index",

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Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry. / Yanina, Irina Y.; Popov, Alexey P.; Bykov, Alexander V.; Meglinski, Igor V.; Tuchin, Valery V.

In: Journal of Biomedical Optics, Vol. 23, No. 1, 016003, 01.2018.

Research output: Contribution to journal › Article › Scientific › peer-review

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AU - Tuchin, Valery V.

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