Strength in numbers: Multivalent dendrons that have an N‐maleimido group at the focal point can be used to construct monodisperse one‐to‐one protein–dendron conjugates. The second generation polyamine dendron with spermine surface groups clearly imparts its high‐affinity DNA binding to a protein of choice.
- protein modifications
Kostiainen, M. A., Szilvay, G., Smith, D. K., Linder, M., & Ikkala, O. (2006). Multivalent dendrons for high-affinity adhesion of proteins to DNA. Angewandte Chemie: International Edition, 45(21), 3538-3542. https://doi.org/10.1002/anie.200504540