Multivalent dendrons for high-affinity adhesion of proteins to DNA

Mauri A. Kostiainen (Corresponding Author), Geza Szilvay, David K. Smith (Corresponding Author), Markus Linder, Olli Ikkala

    Research output: Contribution to journalArticleScientificpeer-review

    64 Citations (Scopus)


    Strength in numbers: Multivalent dendrons that have an N‐maleimido group at the focal point can be used to construct monodisperse one‐to‐one protein–dendron conjugates. The second generation polyamine dendron with spermine surface groups clearly imparts its high‐affinity DNA binding to a protein of choice.
    Original languageEnglish
    Pages (from-to)3538-3542
    Number of pages5
    JournalAngewandte Chemie: International Edition
    Issue number21
    Publication statusPublished - 2006
    MoE publication typeA1 Journal article-refereed


    • dendrimers
    • DNA
    • multivalency
    • protein modifications
    • self-assembly


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