Multivalent dendrons for high-affinity adhesion of proteins to DNA

Mauri A. Kostiainen (Corresponding Author), Geza Szilvay, David K. Smith (Corresponding Author), Markus Linder, Olli Ikkala

    Research output: Contribution to journalArticleScientificpeer-review

    62 Citations (Scopus)

    Abstract

    Strength in numbers: Multivalent dendrons that have an N‐maleimido group at the focal point can be used to construct monodisperse one‐to‐one protein–dendron conjugates. The second generation polyamine dendron with spermine surface groups clearly imparts its high‐affinity DNA binding to a protein of choice.
    Original languageEnglish
    Pages (from-to)3538-3542
    Number of pages5
    JournalAngewandte Chemie: International Edition
    Volume45
    Issue number21
    DOIs
    Publication statusPublished - 2006
    MoE publication typeA1 Journal article-refereed

    Keywords

    • dendrimers
    • DNA
    • multivalency
    • protein modifications
    • self-assembly

    Fingerprint

    Dive into the research topics of 'Multivalent dendrons for high-affinity adhesion of proteins to DNA'. Together they form a unique fingerprint.

    Cite this