Multivariate closed-loop model for analysis of cardiovascular dynamics

Ilkka Korhonen

Research output: Contribution to journalArticleScientificpeer-review

15 Citations (Scopus)


This paper introduces a closed-loop model for the analysis of interactions between heart rate and blood pressure variability, and respiration. The respiratory influence is modeled with an anti-causal structure to control the possible phase lead of heart rate to instantaneous lung volume. The closed-loop structure between heart rate and blood pressure allows the analysis of inter-relationships between the signals. Simulations and results on experimental data show the identifiability of the model and the robustness of the noise source contribution analysis over a wide range of model orders.

Original languageEnglish
Pages (from-to)264-267
JournalMethods of Information in Medicine
Issue number4 - 5
Publication statusPublished - 1997
MoE publication typeA1 Journal article-refereed


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