This paper introduces a closed-loop model for the analysis of interactions between heart rate and blood pressure variability, and respiration. The respiratory influence is modeled with an anti-causal structure to control the possible phase lead of heart rate to instantaneous lung volume. The closed-loop structure between heart rate and blood pressure allows the analysis of inter-relationships between the signals. Simulations and results on experimental data show the identifiability of the model and the robustness of the noise source contribution analysis over a wide range of model orders.
|Journal||Methods of Information in Medicine|
|Issue number||4 - 5|
|Publication status||Published - 1997|
|MoE publication type||A1 Journal article-refereed|