Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection

Vasuki Durairaj; Niklas Wester; Jarkko Etula; Tomi Laurila; Janika Lehtonen; Orlando J. Rojas; Nikolaos Pahimanolis; Jari Koskinen

doi:10.1021/acs.jpcc.9b05537

Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection

Vasuki Durairaj (Corresponding Author), Niklas Wester, Jarkko Etula, Tomi Laurila, Janika Lehtonen, Orlando J. Rojas, Nikolaos Pahimanolis, Jari Koskinen

Not published at VTT

Research output: Contribution to journal › Article › Scientific › peer-review

33 Citations (Scopus)

Abstract

We introduce a composite membrane comprised of multiwalled carbon nanotubes (MWCNTs) dispersed in a matrix of sulfated nanofibrillar cellulose (SNFC) and Nafion. The high negative charge densities of the SNFC and Nafion ionomers enhance the cationic selectivity of the composite. The composite is characterized by scanning electron (SEM) and transmission electron (TEM) microscopies as well as Fourier transform infrared (FTIR) and Raman spectroscopies. Tetrahedral amorphous carbon (ta-C) electrodes modified with the composite are investigated as potential dopamine (DA) electrochemical sensors. The composite-modified electrodes show significant selectivity and sensitivity toward DA in the presence of ascorbic acid (AA) and uric acid (UA) in physiologically relevant concentrations. A linear dopamine detection range of 0.05-100 μM with detection limits of 65 nM in PBS and 107 nM in interferent solution was determined using 100 mV/s cyclic voltammetry (CV) measurements. These results highlight the potential of the composite membrane for in vivo detection of neurotransmitters.

Original language	English
Pages (from-to)	24826–24836
Journal	Journal of Physical Chemistry C
Volume	123
Issue number	40
DOIs	https://doi.org/10.1021/acs.jpcc.9b05537
Publication status	Published - 10 Oct 2019
MoE publication type	A1 Journal article-refereed

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10.1021/acs.jpcc.9b05537

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@article{6698e981126347e9a44a085a243e75bb,

title = "Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection",

abstract = "We introduce a composite membrane comprised of multiwalled carbon nanotubes (MWCNTs) dispersed in a matrix of sulfated nanofibrillar cellulose (SNFC) and Nafion. The high negative charge densities of the SNFC and Nafion ionomers enhance the cationic selectivity of the composite. The composite is characterized by scanning electron (SEM) and transmission electron (TEM) microscopies as well as Fourier transform infrared (FTIR) and Raman spectroscopies. Tetrahedral amorphous carbon (ta-C) electrodes modified with the composite are investigated as potential dopamine (DA) electrochemical sensors. The composite-modified electrodes show significant selectivity and sensitivity toward DA in the presence of ascorbic acid (AA) and uric acid (UA) in physiologically relevant concentrations. A linear dopamine detection range of 0.05-100 μM with detection limits of 65 nM in PBS and 107 nM in interferent solution was determined using 100 mV/s cyclic voltammetry (CV) measurements. These results highlight the potential of the composite membrane for in vivo detection of neurotransmitters.",

author = "Vasuki Durairaj and Niklas Wester and Jarkko Etula and Tomi Laurila and Janika Lehtonen and Rojas, {Orlando J.} and Nikolaos Pahimanolis and Jari Koskinen",

note = "Funding Information: This work was supported by Business Finland funding (previously Tekes-the Finnish Funding Agency for Technology and Innovation) under the projects FEDOC (Grant No. 211637) and PrepIDEA (Grant No. 211755). The authors acknowledge the provision of facilities by Aalto University Bioeconomy and OtaNano – Nanomicroscopy Center (Aalto-NMC) and RawMatters research infrastructure (RAMI). The Academy of Finland Center of Excellence on Molecular Engineering of Biosynthetic Hybrid Materials Research (HYBER) is also acknowledged for supporting this work. Publisher Copyright: {\textcopyright} 2019 American Chemical Society.",

year = "2019",

month = oct,

day = "10",

doi = "10.1021/acs.jpcc.9b05537",

language = "English",

volume = "123",

pages = "24826–24836",

journal = "Journal of Physical Chemistry C",

issn = "1932-7447",

publisher = "American Chemical Society",

number = "40",

}

Durairaj, V, Wester, N, Etula, J, Laurila, T, Lehtonen, J, Rojas, OJ, Pahimanolis, N & Koskinen, J 2019, 'Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection', Journal of Physical Chemistry C, vol. 123, no. 40, pp. 24826–24836. https://doi.org/10.1021/acs.jpcc.9b05537

Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection. / Durairaj, Vasuki (Corresponding Author); Wester, Niklas; Etula, Jarkko et al.
In: Journal of Physical Chemistry C, Vol. 123, No. 40, 10.10.2019, p. 24826–24836.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection

AU - Durairaj, Vasuki

AU - Wester, Niklas

AU - Etula, Jarkko

AU - Laurila, Tomi

AU - Lehtonen, Janika

AU - Rojas, Orlando J.

AU - Pahimanolis, Nikolaos

AU - Koskinen, Jari

N1 - Funding Information: This work was supported by Business Finland funding (previously Tekes-the Finnish Funding Agency for Technology and Innovation) under the projects FEDOC (Grant No. 211637) and PrepIDEA (Grant No. 211755). The authors acknowledge the provision of facilities by Aalto University Bioeconomy and OtaNano – Nanomicroscopy Center (Aalto-NMC) and RawMatters research infrastructure (RAMI). The Academy of Finland Center of Excellence on Molecular Engineering of Biosynthetic Hybrid Materials Research (HYBER) is also acknowledged for supporting this work. Publisher Copyright: © 2019 American Chemical Society.

PY - 2019/10/10

Y1 - 2019/10/10

N2 - We introduce a composite membrane comprised of multiwalled carbon nanotubes (MWCNTs) dispersed in a matrix of sulfated nanofibrillar cellulose (SNFC) and Nafion. The high negative charge densities of the SNFC and Nafion ionomers enhance the cationic selectivity of the composite. The composite is characterized by scanning electron (SEM) and transmission electron (TEM) microscopies as well as Fourier transform infrared (FTIR) and Raman spectroscopies. Tetrahedral amorphous carbon (ta-C) electrodes modified with the composite are investigated as potential dopamine (DA) electrochemical sensors. The composite-modified electrodes show significant selectivity and sensitivity toward DA in the presence of ascorbic acid (AA) and uric acid (UA) in physiologically relevant concentrations. A linear dopamine detection range of 0.05-100 μM with detection limits of 65 nM in PBS and 107 nM in interferent solution was determined using 100 mV/s cyclic voltammetry (CV) measurements. These results highlight the potential of the composite membrane for in vivo detection of neurotransmitters.

AB - We introduce a composite membrane comprised of multiwalled carbon nanotubes (MWCNTs) dispersed in a matrix of sulfated nanofibrillar cellulose (SNFC) and Nafion. The high negative charge densities of the SNFC and Nafion ionomers enhance the cationic selectivity of the composite. The composite is characterized by scanning electron (SEM) and transmission electron (TEM) microscopies as well as Fourier transform infrared (FTIR) and Raman spectroscopies. Tetrahedral amorphous carbon (ta-C) electrodes modified with the composite are investigated as potential dopamine (DA) electrochemical sensors. The composite-modified electrodes show significant selectivity and sensitivity toward DA in the presence of ascorbic acid (AA) and uric acid (UA) in physiologically relevant concentrations. A linear dopamine detection range of 0.05-100 μM with detection limits of 65 nM in PBS and 107 nM in interferent solution was determined using 100 mV/s cyclic voltammetry (CV) measurements. These results highlight the potential of the composite membrane for in vivo detection of neurotransmitters.

UR - http://www.scopus.com/inward/record.url?scp=85072975484&partnerID=8YFLogxK

U2 - 10.1021/acs.jpcc.9b05537

DO - 10.1021/acs.jpcc.9b05537

M3 - Article

SN - 1932-7447

VL - 123

SP - 24826

EP - 24836

JO - Journal of Physical Chemistry C

JF - Journal of Physical Chemistry C

IS - 40

ER -

Multiwalled Carbon Nanotubes/Nanofibrillar Cellulose/Nafion Composite-Modified Tetrahedral Amorphous Carbon Electrodes for Selective Dopamine Detection

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