Natural surfactants towards a more sustainable fluorine chemistry

V. Dichiarante (Corresponding Author), R. Milani, P. Metrangolo (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

10 Citations (Scopus)

Abstract

Fluorinated materials play an essential role in modern industry and technology, and their importance is expected to grow even more in the near future. Unfortunately, their practical application often requires dispersion by means of fluorinated surfactants, which raised huge environmental and toxicity concerns due to their long-lasting persistence in the environment and high tendency to accumulate in animals and humans. A greener and more sustainable strategy towards the replacement of synthetic fluorosurfactants is offered by the use of amphiphiles of biological origin. Among them, phospholipids have been the most widely exploited as emulsifiers of fluorous compounds. Some interesting examples were also reported using amphiphilic proteins, in particular fungal hydrophobins, as biosurfactants and coating agents for fluorinated substrates. This perspective offers an overview of the main natural surfactants currently used in fluorine chemistry, focusing in particular on two main application areas: (i) fluorous oil-in-water emulsions and gas microbubbles for biomedical imaging and drug delivery, and (ii) coating and functionalization of solid fluorinated surfaces.

Original languageEnglish
Pages (from-to)13-27
Number of pages15
JournalGreen Chemistry
Volume20
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018
MoE publication typeA1 Journal article-refereed

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Fluorine
fluorine
Surface-Active Agents
surfactant
coating
Surface active agents
Coatings
Amphiphiles
Phospholipids
emulsion
Emulsions
phospholipid
Drug delivery
Toxicity
Oils
Animals
drug
persistence
replacement
Gases

Cite this

Dichiarante, V. ; Milani, R. ; Metrangolo, P. / Natural surfactants towards a more sustainable fluorine chemistry. In: Green Chemistry. 2018 ; Vol. 20, No. 1. pp. 13-27.
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Natural surfactants towards a more sustainable fluorine chemistry. / Dichiarante, V. (Corresponding Author); Milani, R.; Metrangolo, P. (Corresponding Author).

In: Green Chemistry, Vol. 20, No. 1, 01.01.2018, p. 13-27.

Research output: Contribution to journalArticleScientificpeer-review

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AU - Milani, R.

AU - Metrangolo, P.

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AB - Fluorinated materials play an essential role in modern industry and technology, and their importance is expected to grow even more in the near future. Unfortunately, their practical application often requires dispersion by means of fluorinated surfactants, which raised huge environmental and toxicity concerns due to their long-lasting persistence in the environment and high tendency to accumulate in animals and humans. A greener and more sustainable strategy towards the replacement of synthetic fluorosurfactants is offered by the use of amphiphiles of biological origin. Among them, phospholipids have been the most widely exploited as emulsifiers of fluorous compounds. Some interesting examples were also reported using amphiphilic proteins, in particular fungal hydrophobins, as biosurfactants and coating agents for fluorinated substrates. This perspective offers an overview of the main natural surfactants currently used in fluorine chemistry, focusing in particular on two main application areas: (i) fluorous oil-in-water emulsions and gas microbubbles for biomedical imaging and drug delivery, and (ii) coating and functionalization of solid fluorinated surfaces.

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