New functional foods in the treatment of food allergy

Erika Isolauri (Corresponding Author), Seppo Salminen, Tiina Mattila-Sandholm

    Research output: Contribution to journalArticleScientificpeer-review

    41 Citations (Scopus)

    Abstract

    Over the last two decades atopic diseases have increased in prevalence and severity in the industrialized countries. Food allergy is frequently the first manifestation of these disorders. Currently food allergy is mainly treated with elimination diets. However, this approach to control allergic inflammation by empirical elimination diets has not proved totally satisfactory. Applying therapeutic elimination diets in clinically documented allergy to a specific food has been shown to alleviate symptoms and reverse some disturbances of humoral and cell-mediated immune response. These diets are, however, associated with the risk of inadequate nutrition in infants with allergies to foods of vital importance. New approaches to the management of food allergy, such as for example immunotherapy for counteracting the hypersensitivity process and for potentiating the gut barrier mechanisms, are therefore needed. Diet remains an important element in this approach as sensitization to dietary antigens is frequently transient and is reversed to antigen-specific hyporesponsiveness. However, it represents an initial link in the development of more permanent sensitization to aeroallergens.
    Original languageEnglish
    Pages (from-to)299-302
    Number of pages4
    JournalAnnals of Medicine
    Volume31
    Issue number4
    DOIs
    Publication statusPublished - 1999
    MoE publication typeA1 Journal article-refereed

    Fingerprint

    Functional Food
    Food Hypersensitivity
    Diet
    Hypersensitivity
    Therapeutics
    Antigens
    Developed Countries
    Immunotherapy
    Inflammation
    Food

    Keywords

    • atopy
    • diet
    • food allergy
    • nutrition

    Cite this

    Isolauri, Erika ; Salminen, Seppo ; Mattila-Sandholm, Tiina. / New functional foods in the treatment of food allergy. In: Annals of Medicine. 1999 ; Vol. 31, No. 4. pp. 299-302.
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    New functional foods in the treatment of food allergy. / Isolauri, Erika (Corresponding Author); Salminen, Seppo; Mattila-Sandholm, Tiina.

    In: Annals of Medicine, Vol. 31, No. 4, 1999, p. 299-302.

    Research output: Contribution to journalArticleScientificpeer-review

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    AU - Salminen, Seppo

    AU - Mattila-Sandholm, Tiina

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    AB - Over the last two decades atopic diseases have increased in prevalence and severity in the industrialized countries. Food allergy is frequently the first manifestation of these disorders. Currently food allergy is mainly treated with elimination diets. However, this approach to control allergic inflammation by empirical elimination diets has not proved totally satisfactory. Applying therapeutic elimination diets in clinically documented allergy to a specific food has been shown to alleviate symptoms and reverse some disturbances of humoral and cell-mediated immune response. These diets are, however, associated with the risk of inadequate nutrition in infants with allergies to foods of vital importance. New approaches to the management of food allergy, such as for example immunotherapy for counteracting the hypersensitivity process and for potentiating the gut barrier mechanisms, are therefore needed. Diet remains an important element in this approach as sensitization to dietary antigens is frequently transient and is reversed to antigen-specific hyporesponsiveness. However, it represents an initial link in the development of more permanent sensitization to aeroallergens.

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