@inproceedings{875d5b6a2f00428eb97bfbf42c472ef3,
title = "Noninvasive control of rhodamine-loaded capsules distribution in vivo",
abstract = "Using fluorescence spectroscopy system with fibre-optical probe, we investigated the dynamics of propagation and circulation in the microcirculatory system of experimental nanocapsules fluorescent-labelled (rhodamine TRITC) nanocapsules. The studies were carried out in clinically healthy Wistar rats. The model animals were divided into control group and group received injections of the nanocapsules. The fluorescent measurements conducted transcutaneously on the thigh surface. The administration of the preparation with the rhodamine concentration of 5 mg/kg of animal weight resulted in twofold increase of fluorescence intensity by reference to the baseline level. As a result of the study, it was concluded that fluorescence spectroscopy can be used for transdermal measurements of the rhodamine-loaded capsules in vivo.",
keywords = "blood microcirculation, drug delivery, fluorescence spectroscopy, fluorescent labelled particles, nanocomposite polymeric capsules, optical measurements in vivo, rhodamine TRITC",
author = "O. Stelmashchuk and Y. Tarakanchikova and E. Seryogina and G. Piavchenko and E. Zherebtsov and A. Dunaev and Alexey Popov and I. Meglinski",
year = "2018",
month = apr,
day = "26",
doi = "10.1117/12.2315773",
language = "English",
isbn = "978-1-51062-001-8",
series = "Progress in Biomedical Optics and Imaging",
publisher = "International Society for Optics and Photonics SPIE",
number = "56",
editor = "Genina, {Elina A.} and Goryacheva, {Irina Yu.} and Tuchin, {Valery V.}",
booktitle = "Saratov Fall Meeting 2017",
address = "United States",
note = "Saratov Fall Meeting 2017 : Optical Technologies in Biophysics and Medicine XIX ; Conference date: 26-09-2017 Through 30-09-2017",
}