@inproceedings{875d5b6a2f00428eb97bfbf42c472ef3,
title = "Noninvasive control of rhodamine-loaded capsules distribution in vivo",
abstract = "Using fluorescence spectroscopy system with fibre-optical probe, we investigated the dynamics of propagation and circulation in the microcirculatory system of experimental nanocapsules fluorescent-labelled (rhodamine TRITC) nanocapsules. The studies were carried out in clinically healthy Wistar rats. The model animals were divided into control group and group received injections of the nanocapsules. The fluorescent measurements conducted transcutaneously on the thigh surface. The administration of the preparation with the rhodamine concentration of 5 mg/kg of animal weight resulted in twofold increase of fluorescence intensity by reference to the baseline level. As a result of the study, it was concluded that fluorescence spectroscopy can be used for transdermal measurements of the rhodamine-loaded capsules in vivo.",
keywords = "blood microcirculation, drug delivery, fluorescence spectroscopy, fluorescent labelled particles, nanocomposite polymeric capsules, optical measurements in vivo, rhodamine TRITC",
author = "O. Stelmashchuk and Y. Tarakanchikova and E. Seryogina and G. Piavchenko and E. Zherebtsov and A. Dunaev and Alexey Popov and I. Meglinski",
note = "Funding Information: This work was supported by the Russian Foundation on Innovations U.M.N.I.K., 2017 SPIE Optics and Photonics Education Scholarship, CIMO Fellowship (TM-15-9729, YT), EDUFI Fellowship (TM-17-10389, YT), Russian Government (grant No. 074-U01, AP, IM), Russian Science Foundation (grant No. 15-14-10008, IM), MEPhI Academic Excellence Project (Contract No. 02.a03.21.0005, IM), Academy of Finland (grant No. 290596, AP). EZ kindly acknowledges the funding from the European Union{\textquoteright}s Horizon 2020 Research and Innovation Program under grant agreement No. 703145. Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Saratov Fall Meeting 2017 : Optical Technologies in Biophysics and Medicine XIX ; Conference date: 26-09-2017 Through 30-09-2017",
year = "2018",
month = apr,
day = "26",
doi = "10.1117/12.2315773",
language = "English",
isbn = "978-1-51062-001-8",
series = "Progress in Biomedical Optics and Imaging",
publisher = "International Society for Optics and Photonics SPIE",
number = "56",
editor = "Genina, {Elina A.} and Goryacheva, {Irina Yu.} and Tuchin, {Valery V.}",
booktitle = "Saratov Fall Meeting 2017",
address = "United States",
}