One compartment fermentation model

Anna Marja Aura; Johanna Maukonen

doi:10.1007/978-3-319-16104-4_25

One compartment fermentation model

Anna Marja Aura^*, Johanna Maukonen

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Scientific › peer-review

8 Citations (Scopus)

Abstract

In vitro colon model was first applied in an inter-laboratory dietary fibre (DF) fermentation study and adapted at VTT for whole foods and beverages, isolated dietary phenolic compounds and pharmaceuticals. The application of the models includes strict anaerobiosis, which ensures active anaerobic microbial community. Pooling of faecal samples from several donors ensures reproducibility between the experiments. The correlation of in vitro data with in vivo data is quantitatively challenging, but is qualitatively highly relevant. In this chapter we explain the applicability of the one compartment fermentation model, including the general protocol as well as the advantages and disadvantages of the system.

Original language	English
Title of host publication	The Impact of Food Bioactives on Health
Subtitle of host publication	In Vitro and Ex Vivo Models
Editors	K. Verhoeckx, et al.
Publisher	Springer
Pages	281-292
Number of pages	12
ISBN (Electronic)	978-3-319-16104-4
ISBN (Print)	978-3-319-15791-7
DOIs	https://doi.org/10.1007/978-3-319-16104-4_25
Publication status	Published - 1 Jan 2015
MoE publication type	A3 Part of a book or another research book

Keywords

Anaerobic conditions
Dietary fibre
Human faecal microbiota
Microbial metabolites
One compartment colon in vitro model
SCFA

Access to Document

10.1007/978-3-319-16104-4_25

Cite this

@inbook{500eb9b5e4844fd69ed40987203c1d4a,

title = "One compartment fermentation model",

abstract = "In vitro colon model was first applied in an inter-laboratory dietary fibre (DF) fermentation study and adapted at VTT for whole foods and beverages, isolated dietary phenolic compounds and pharmaceuticals. The application of the models includes strict anaerobiosis, which ensures active anaerobic microbial community. Pooling of faecal samples from several donors ensures reproducibility between the experiments. The correlation of in vitro data with in vivo data is quantitatively challenging, but is qualitatively highly relevant. In this chapter we explain the applicability of the one compartment fermentation model, including the general protocol as well as the advantages and disadvantages of the system.",

keywords = "Anaerobic conditions, Dietary fibre, Human faecal microbiota, Microbial metabolites, One compartment colon in vitro model, SCFA",

author = "Aura, {Anna Marja} and Johanna Maukonen",

year = "2015",

month = jan,

day = "1",

doi = "10.1007/978-3-319-16104-4_25",

language = "English",

isbn = "978-3-319-15791-7",

pages = "281--292",

editor = "K. Verhoeckx and {et al.}",

booktitle = "The Impact of Food Bioactives on Health",

publisher = "Springer",

address = "Germany",

}

TY - CHAP

T1 - One compartment fermentation model

AU - Aura, Anna Marja

AU - Maukonen, Johanna

PY - 2015/1/1

Y1 - 2015/1/1

N2 - In vitro colon model was first applied in an inter-laboratory dietary fibre (DF) fermentation study and adapted at VTT for whole foods and beverages, isolated dietary phenolic compounds and pharmaceuticals. The application of the models includes strict anaerobiosis, which ensures active anaerobic microbial community. Pooling of faecal samples from several donors ensures reproducibility between the experiments. The correlation of in vitro data with in vivo data is quantitatively challenging, but is qualitatively highly relevant. In this chapter we explain the applicability of the one compartment fermentation model, including the general protocol as well as the advantages and disadvantages of the system.

AB - In vitro colon model was first applied in an inter-laboratory dietary fibre (DF) fermentation study and adapted at VTT for whole foods and beverages, isolated dietary phenolic compounds and pharmaceuticals. The application of the models includes strict anaerobiosis, which ensures active anaerobic microbial community. Pooling of faecal samples from several donors ensures reproducibility between the experiments. The correlation of in vitro data with in vivo data is quantitatively challenging, but is qualitatively highly relevant. In this chapter we explain the applicability of the one compartment fermentation model, including the general protocol as well as the advantages and disadvantages of the system.

KW - Anaerobic conditions

KW - Dietary fibre

KW - Human faecal microbiota

KW - Microbial metabolites

KW - One compartment colon in vitro model

KW - SCFA

UR - http://www.scopus.com/inward/record.url?scp=84945157895&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-16104-4_25

DO - 10.1007/978-3-319-16104-4_25

M3 - Chapter or book article

AN - SCOPUS:84945157895

SN - 978-3-319-15791-7

SP - 281

EP - 292

BT - The Impact of Food Bioactives on Health

A2 - Verhoeckx, K.

A2 - , et al.

PB - Springer

ER -

One compartment fermentation model

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this