Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection

Yunfeng Nie; Sanna Aikio; Annukka Kokkonen; Teemu Sipola; Sanna Uusitalo; Simonetta Grilli; Heidi Ottevaere

doi:10.1364/MICROSCOPY.2020.MTh4A.3

Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection

Yunfeng Nie^*
, Sanna Aikio
, Annukka Kokkonen
, Teemu Sipola
, Sanna Uusitalo
, Simonetta Grilli
, Heidi Ottevaere

^*Corresponding author for this work

Vrije Universiteit Brussel
National Research Council (CNR)

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

Abstract

Current commercial fluorescence microscopes are typically sophisticated, bulky and expensive, not suitable for low-volume and/or clinic routine biomedical detection, e.g. lab-on-chip devices. We present optical design strategies and the principle demonstrator of a miniature fluorescence microscope aiming for super-sensitive detection.

Original language	English
Title of host publication	Microscopy Histopathology and Analytics, Microscopy 2020
Publisher	Optica Publishing Group
ISBN (Electronic)	978-1-943580-74-3
DOIs	https://doi.org/10.1364/MICROSCOPY.2020.MTh4A.3
Publication status	Published - 2020
MoE publication type	A4 Article in a conference publication
Event	Microscopy Histopathology and Analytics, Microscopy 2020 - Washington, United States Duration: 20 Apr 2020 → 23 Apr 2020

Publication series

Series	OSA Technical Digest

Conference

Conference	Microscopy Histopathology and Analytics, Microscopy 2020
Country/Territory	United States
City	Washington
Period	20/04/20 → 23/04/20

Funding

The authors acknowledge the EU funding within the Horizon 2020 Program, under the “SensApp”, Grant Agreement n.829104.

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10.1364/MICROSCOPY.2020.MTh4A.3

Cite this

@inproceedings{ff037d49015246df86b3433d7376a2a7,

title = "Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection",

abstract = "Current commercial fluorescence microscopes are typically sophisticated, bulky and expensive, not suitable for low-volume and/or clinic routine biomedical detection, e.g. lab-on-chip devices. We present optical design strategies and the principle demonstrator of a miniature fluorescence microscope aiming for super-sensitive detection.",

author = "Yunfeng Nie and Sanna Aikio and Annukka Kokkonen and Teemu Sipola and Sanna Uusitalo and Simonetta Grilli and Heidi Ottevaere",

year = "2020",

doi = "10.1364/MICROSCOPY.2020.MTh4A.3",

language = "English",

series = "OSA Technical Digest",

publisher = "Optica Publishing Group",

booktitle = "Microscopy Histopathology and Analytics, Microscopy 2020",

address = "United States",

note = "Microscopy Histopathology and Analytics, Microscopy 2020 ; Conference date: 20-04-2020 Through 23-04-2020",

}

Nie, Y, Aikio, S , Kokkonen, A , Sipola, T, Uusitalo, S, Grilli, S & Ottevaere, H 2020, Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection. in Microscopy Histopathology and Analytics, Microscopy 2020., MTh4A.3, Optica Publishing Group, OSA Technical Digest, Microscopy Histopathology and Analytics, Microscopy 2020, Washington, United States, 20/04/20. https://doi.org/10.1364/MICROSCOPY.2020.MTh4A.3

Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection. / Nie, Yunfeng; Aikio, Sanna ; Kokkonen, Annukka et al.
Microscopy Histopathology and Analytics, Microscopy 2020. Optica Publishing Group, 2020. MTh4A.3 (OSA Technical Digest).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

TY - GEN

T1 - Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection

AU - Nie, Yunfeng

AU - Aikio, Sanna

AU - Kokkonen, Annukka

AU - Sipola, Teemu

AU - Uusitalo, Sanna

AU - Grilli, Simonetta

AU - Ottevaere, Heidi

PY - 2020

Y1 - 2020

N2 - Current commercial fluorescence microscopes are typically sophisticated, bulky and expensive, not suitable for low-volume and/or clinic routine biomedical detection, e.g. lab-on-chip devices. We present optical design strategies and the principle demonstrator of a miniature fluorescence microscope aiming for super-sensitive detection.

AB - Current commercial fluorescence microscopes are typically sophisticated, bulky and expensive, not suitable for low-volume and/or clinic routine biomedical detection, e.g. lab-on-chip devices. We present optical design strategies and the principle demonstrator of a miniature fluorescence microscope aiming for super-sensitive detection.

UR - https://www.scopus.com/pages/publications/85091395196

U2 - 10.1364/MICROSCOPY.2020.MTh4A.3

DO - 10.1364/MICROSCOPY.2020.MTh4A.3

M3 - Conference article in proceedings

AN - SCOPUS:85091395196

T3 - OSA Technical Digest

BT - Microscopy Histopathology and Analytics, Microscopy 2020

PB - Optica Publishing Group

T2 - Microscopy Histopathology and Analytics, Microscopy 2020

Y2 - 20 April 2020 through 23 April 2020

ER -

Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection

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