Optimal sizes of gold nanoparticles for laser treatment of tumors

Alexey P. Popov, Alexander V. Priezzhev, Risto Myllylä

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

5 Citations (Scopus)

Abstract

In the present paper, the problem of laser treatment of tumors by means of gold nanoparticles is discussed. One of the mechanisms of cancerous cells destruction is formation of small bubbles on cell membranes and inside cells around gold nanoparticles induced by laser pulse absorption by the particles. It is shown by Mie theory calculations that the optimal spectral region for such tumor treatment is within 400 - 550 nm with the corresponding nanoparticles sizes to be 30 - 40 nm. The appropriate durations of laser pulses for such kind of laser therapy are under 1 ns in this spectral region.

Original languageEnglish
Title of host publicationFifth International Conference on Photonics and Imaging in Biology and Medicine
EditorsQingming Luo, Lihong V. Wang, Valery V. Tuchin, Min Gu
PublisherInternational Society for Optics and Photonics SPIE
Volume2
ISBN (Print)978-0-8194-6656-3
DOIs
Publication statusPublished - 5 Nov 2007
MoE publication typeNot Eligible
EventFifth International Conference on Photonics and Imaging in Biology and Medicine - Wuhan, China
Duration: 1 Sep 20063 Sep 2006

Publication series

SeriesProgress in Biomedical Optics and Imaging
Number36
Volume8
ISSN1605-7422
SeriesProceedings of SPIE
Volume6534
ISSN0277-786X

Conference

ConferenceFifth International Conference on Photonics and Imaging in Biology and Medicine
CountryChina
CityWuhan
Period1/09/063/09/06

Keywords

  • Bubble formation
  • Cancer
  • Gold nanoparticles
  • Laser
  • Photothermolysis

Fingerprint Dive into the research topics of 'Optimal sizes of gold nanoparticles for laser treatment of tumors'. Together they form a unique fingerprint.

  • Cite this

    Popov, A. P., Priezzhev, A. V., & Myllylä, R. (2007). Optimal sizes of gold nanoparticles for laser treatment of tumors. In Q. Luo, L. V. Wang, V. V. Tuchin, & M. Gu (Eds.), Fifth International Conference on Photonics and Imaging in Biology and Medicine (Vol. 2). [65343K] International Society for Optics and Photonics SPIE. Progress in Biomedical Optics and Imaging, No. 36, Vol.. 8, Proceedings of SPIE, Vol.. 6534 https://doi.org/10.1117/12.741501