Optimal sizes of gold nanoparticles for laser treatment of tumors

Alexey P. Popov; Alexander V. Priezzhev; Risto Myllylä

doi:10.1117/12.741501

Optimal sizes of gold nanoparticles for laser treatment of tumors

Alexey P. Popov^*, Alexander V. Priezzhev, Risto Myllylä

^*Corresponding author for this work

Not published at VTT

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

7 Citations (Scopus)

Abstract

In the present paper, the problem of laser treatment of tumors by means of gold nanoparticles is discussed. One of the mechanisms of cancerous cells destruction is formation of small bubbles on cell membranes and inside cells around gold nanoparticles induced by laser pulse absorption by the particles. It is shown by Mie theory calculations that the optimal spectral region for such tumor treatment is within 400 - 550 nm with the corresponding nanoparticles sizes to be 30 - 40 nm. The appropriate durations of laser pulses for such kind of laser therapy are under 1 ns in this spectral region.

Original language	English
Title of host publication	Fifth International Conference on Photonics and Imaging in Biology and Medicine
Editors	Qingming Luo, Lihong V. Wang, Valery V. Tuchin, Min Gu
Publisher	International Society for Optics and Photonics SPIE
Volume	2
ISBN (Print)	978-0-8194-6656-3
DOIs	https://doi.org/10.1117/12.741501
Publication status	Published - 5 Nov 2007
MoE publication type	Not Eligible
Event	Fifth International Conference on Photonics and Imaging in Biology and Medicine - Wuhan, China Duration: 1 Sept 2006 → 3 Sept 2006

Publication series

Series	Progress in Biomedical Optics and Imaging
Number	36
Volume	8
ISSN	1605-7422

Series	Proceedings of SPIE
Volume	6534
ISSN	0277-786X

Conference

Conference	Fifth International Conference on Photonics and Imaging in Biology and Medicine
Country/Territory	China
City	Wuhan
Period	1/09/06 → 3/09/06

Keywords

Bubble formation
Cancer
Gold nanoparticles
Laser
Photothermolysis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1117/12.741501

Cite this

Popov, Alexey P. ; Priezzhev, Alexander V. ; Myllylä, Risto. / Optimal sizes of gold nanoparticles for laser treatment of tumors. Fifth International Conference on Photonics and Imaging in Biology and Medicine. editor / Qingming Luo ; Lihong V. Wang ; Valery V. Tuchin ; Min Gu. Vol. 2 International Society for Optics and Photonics SPIE, 2007. (Progress in Biomedical Optics and Imaging; No. 36, Vol. 8). (Proceedings of SPIE, Vol. 6534).

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title = "Optimal sizes of gold nanoparticles for laser treatment of tumors",

abstract = "In the present paper, the problem of laser treatment of tumors by means of gold nanoparticles is discussed. One of the mechanisms of cancerous cells destruction is formation of small bubbles on cell membranes and inside cells around gold nanoparticles induced by laser pulse absorption by the particles. It is shown by Mie theory calculations that the optimal spectral region for such tumor treatment is within 400 - 550 nm with the corresponding nanoparticles sizes to be 30 - 40 nm. The appropriate durations of laser pulses for such kind of laser therapy are under 1 ns in this spectral region.",

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author = "Popov, {Alexey P.} and Priezzhev, {Alexander V.} and Risto Myllyl{\"a}",

year = "2007",

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day = "5",

doi = "10.1117/12.741501",

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publisher = "International Society for Optics and Photonics SPIE",

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Popov, AP, Priezzhev, AV & Myllylä, R 2007, Optimal sizes of gold nanoparticles for laser treatment of tumors. in Q Luo, LV Wang, VV Tuchin & M Gu (eds), Fifth International Conference on Photonics and Imaging in Biology and Medicine. vol. 2, 65343K, International Society for Optics and Photonics SPIE, Progress in Biomedical Optics and Imaging, no. 36, vol. 8, Proceedings of SPIE, vol. 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, Wuhan, China, 1/09/06. https://doi.org/10.1117/12.741501

Optimal sizes of gold nanoparticles for laser treatment of tumors. / Popov, Alexey P.; Priezzhev, Alexander V.; Myllylä, Risto.
Fifth International Conference on Photonics and Imaging in Biology and Medicine. ed. / Qingming Luo; Lihong V. Wang; Valery V. Tuchin; Min Gu. Vol. 2 International Society for Optics and Photonics SPIE, 2007. 65343K (Progress in Biomedical Optics and Imaging; No. 36, Vol. 8). (Proceedings of SPIE, Vol. 6534).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

TY - GEN

T1 - Optimal sizes of gold nanoparticles for laser treatment of tumors

AU - Popov, Alexey P.

AU - Priezzhev, Alexander V.

AU - Myllylä, Risto

PY - 2007/11/5

Y1 - 2007/11/5

N2 - In the present paper, the problem of laser treatment of tumors by means of gold nanoparticles is discussed. One of the mechanisms of cancerous cells destruction is formation of small bubbles on cell membranes and inside cells around gold nanoparticles induced by laser pulse absorption by the particles. It is shown by Mie theory calculations that the optimal spectral region for such tumor treatment is within 400 - 550 nm with the corresponding nanoparticles sizes to be 30 - 40 nm. The appropriate durations of laser pulses for such kind of laser therapy are under 1 ns in this spectral region.

AB - In the present paper, the problem of laser treatment of tumors by means of gold nanoparticles is discussed. One of the mechanisms of cancerous cells destruction is formation of small bubbles on cell membranes and inside cells around gold nanoparticles induced by laser pulse absorption by the particles. It is shown by Mie theory calculations that the optimal spectral region for such tumor treatment is within 400 - 550 nm with the corresponding nanoparticles sizes to be 30 - 40 nm. The appropriate durations of laser pulses for such kind of laser therapy are under 1 ns in this spectral region.

KW - Bubble formation

KW - Cancer

KW - Gold nanoparticles

KW - Laser

KW - Photothermolysis

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DO - 10.1117/12.741501

M3 - Conference article in proceedings

AN - SCOPUS:35648980419

SN - 978-0-8194-6656-3

VL - 2

T3 - Progress in Biomedical Optics and Imaging

BT - Fifth International Conference on Photonics and Imaging in Biology and Medicine

A2 - Luo, Qingming

A2 - Wang, Lihong V.

A2 - Tuchin, Valery V.

A2 - Gu, Min

PB - International Society for Optics and Photonics SPIE

T2 - Fifth International Conference on Photonics and Imaging in Biology and Medicine

Y2 - 1 September 2006 through 3 September 2006

ER -

Popov AP, Priezzhev AV, Myllylä R. Optimal sizes of gold nanoparticles for laser treatment of tumors. In Luo Q, Wang LV, Tuchin VV, Gu M, editors, Fifth International Conference on Photonics and Imaging in Biology and Medicine. Vol. 2. International Society for Optics and Photonics SPIE. 2007. 65343K. (Progress in Biomedical Optics and Imaging; No. 36, Vol. 8). (Proceedings of SPIE, Vol. 6534). doi: 10.1117/12.741501

Optimal sizes of gold nanoparticles for laser treatment of tumors

Abstract

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Keywords

UN SDGs

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