Oxazoline-containing phosphazene derivatives, part III

Synthesis and characterization of novel cyclophosphazenes functionalized with chiral 2-oxazoline groups

Luisa Fiocca, Riccardo Pó, Giorgio Giannotta, Mario Gleria, Alfonso Venzo, Roberto Milani, Giovanni Depaoli

Research output: Contribution to journalArticleScientificpeer-review

4 Citations (Scopus)

Abstract

In this paper we describe the synthesis and the characterization of a series of cyclophosphazenes substituted with 2-oxazoline-containing moieties, with and without optical activity. These products could be obtained by reacting cyclophosphazenes containing six (hexachlorocyclophosphazene, C-6-Cl), two (2,2-dichloro-4,4,6,6-bis[spiro(2′,2″-dioxy-1′, 1″-biphenyl)]cyclophosphazene, C-2-Cl) and one (pentakis(phenoxy) monochlorocyclophosphazene, C-1-Cl) chlorine atoms, respectively, with a series of 4-hydroxyphenyl-2-oxazolines, as obtained by condensation reaction of methyl-4-hydroxybenzoate with 2-aminoethanol and with chiral and racemic 1-amino-2-propanol, and successive cyclization reactions of the resulting hydroxyamides to 2-oxazoline compounds.

Original languageEnglish
Pages (from-to)243-260
Number of pages18
JournalDesigned Monomers and Polymers
Volume11
Issue number3
DOIs
Publication statusPublished - 2008
MoE publication typeA1 Journal article-refereed

Fingerprint

Ethanolamine
Condensation reactions
Cyclization
Chlorine
Propanol
Derivatives
Atoms
monoisopropanolamine
diphenyl
methylparaben

Keywords

  • Condensation
  • Cyclophosphazene
  • Optical activity
  • Oxazoline

Cite this

Fiocca, Luisa ; Pó, Riccardo ; Giannotta, Giorgio ; Gleria, Mario ; Venzo, Alfonso ; Milani, Roberto ; Depaoli, Giovanni. / Oxazoline-containing phosphazene derivatives, part III : Synthesis and characterization of novel cyclophosphazenes functionalized with chiral 2-oxazoline groups. In: Designed Monomers and Polymers. 2008 ; Vol. 11, No. 3. pp. 243-260.
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abstract = "In this paper we describe the synthesis and the characterization of a series of cyclophosphazenes substituted with 2-oxazoline-containing moieties, with and without optical activity. These products could be obtained by reacting cyclophosphazenes containing six (hexachlorocyclophosphazene, C-6-Cl), two (2,2-dichloro-4,4,6,6-bis[spiro(2′,2″-dioxy-1′, 1″-biphenyl)]cyclophosphazene, C-2-Cl) and one (pentakis(phenoxy) monochlorocyclophosphazene, C-1-Cl) chlorine atoms, respectively, with a series of 4-hydroxyphenyl-2-oxazolines, as obtained by condensation reaction of methyl-4-hydroxybenzoate with 2-aminoethanol and with chiral and racemic 1-amino-2-propanol, and successive cyclization reactions of the resulting hydroxyamides to 2-oxazoline compounds.",
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Oxazoline-containing phosphazene derivatives, part III : Synthesis and characterization of novel cyclophosphazenes functionalized with chiral 2-oxazoline groups. / Fiocca, Luisa; Pó, Riccardo; Giannotta, Giorgio; Gleria, Mario; Venzo, Alfonso; Milani, Roberto; Depaoli, Giovanni.

In: Designed Monomers and Polymers, Vol. 11, No. 3, 2008, p. 243-260.

Research output: Contribution to journalArticleScientificpeer-review

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T1 - Oxazoline-containing phosphazene derivatives, part III

T2 - Synthesis and characterization of novel cyclophosphazenes functionalized with chiral 2-oxazoline groups

AU - Fiocca, Luisa

AU - Pó, Riccardo

AU - Giannotta, Giorgio

AU - Gleria, Mario

AU - Venzo, Alfonso

AU - Milani, Roberto

AU - Depaoli, Giovanni

PY - 2008

Y1 - 2008

N2 - In this paper we describe the synthesis and the characterization of a series of cyclophosphazenes substituted with 2-oxazoline-containing moieties, with and without optical activity. These products could be obtained by reacting cyclophosphazenes containing six (hexachlorocyclophosphazene, C-6-Cl), two (2,2-dichloro-4,4,6,6-bis[spiro(2′,2″-dioxy-1′, 1″-biphenyl)]cyclophosphazene, C-2-Cl) and one (pentakis(phenoxy) monochlorocyclophosphazene, C-1-Cl) chlorine atoms, respectively, with a series of 4-hydroxyphenyl-2-oxazolines, as obtained by condensation reaction of methyl-4-hydroxybenzoate with 2-aminoethanol and with chiral and racemic 1-amino-2-propanol, and successive cyclization reactions of the resulting hydroxyamides to 2-oxazoline compounds.

AB - In this paper we describe the synthesis and the characterization of a series of cyclophosphazenes substituted with 2-oxazoline-containing moieties, with and without optical activity. These products could be obtained by reacting cyclophosphazenes containing six (hexachlorocyclophosphazene, C-6-Cl), two (2,2-dichloro-4,4,6,6-bis[spiro(2′,2″-dioxy-1′, 1″-biphenyl)]cyclophosphazene, C-2-Cl) and one (pentakis(phenoxy) monochlorocyclophosphazene, C-1-Cl) chlorine atoms, respectively, with a series of 4-hydroxyphenyl-2-oxazolines, as obtained by condensation reaction of methyl-4-hydroxybenzoate with 2-aminoethanol and with chiral and racemic 1-amino-2-propanol, and successive cyclization reactions of the resulting hydroxyamides to 2-oxazoline compounds.

KW - Condensation

KW - Cyclophosphazene

KW - Optical activity

KW - Oxazoline

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