Particle-into-liquid sampler on-line coupled with solid-phase extraction-liquid chromatography-mass spectrometry for the determination of organic acids in atmospheric aerosols

Jevgeni Parshintseva, Maarit Kivilompolo, Jose Ruiz-Jimenez, Kari Hartonen, Markku Kulmala, Marja-Liisa Riekkola (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

17 Citations (Scopus)

Abstract

In the present study, sample collection and preparation were directly integrated with a chromatographic system by coupling a particle-into-liquid sampler for the first time on-line with solid-phase extraction-liquid chromatography–tandem mass spectrometry. Several organic acids, such as adipic, hydroxyglutaric, mandelic, vanillic, cis-pinonic, pinic, azelaic and sebacic, were used in the research. For sample pretreatment and concentration, strong anion exchange material was used in the extraction. Sampling, extraction and analysis conditions were optimized to obtain reliable information about aerosol chemical composition. To evaluate the performance of the on-line coupled system, half of each sample was analysed on-line and the other half was derivatized and analysed off-line by gas chromatography–mass spectrometry. Comparison of the two techniques with use of t-test showed the results to be in an excellent agreement. Limits of detection of studied acids in on-line system were between 0.1 and 0.9 ng. The on-line coupled system is fast and reliable and a promising tool for the real time analysis of organic acids in atmospheric aerosols.
Original languageEnglish
Pages (from-to)5427-5433
JournalJournal of Chromatography A
Volume1217
Issue number33
DOIs
Publication statusPublished - 2010
MoE publication typeA1 Journal article-refereed

Fingerprint

Online Systems
Atmospheric aerosols
Organic acids
Solid Phase Extraction
Liquid chromatography
Aerosols
Liquid Chromatography
Mass spectrometry
Mass Spectrometry
Acids
Liquids
Online systems
Spectrometry
Anions
Limit of Detection
Spectrum Analysis
Ion exchange
Gases
Sampling
Chemical analysis

Keywords

  • On-line coupling
  • Particle-into-liquid sampler
  • Solid-phase extraction
  • Organic acids
  • Atmospheric aerosols
  • HPLC-MS

Cite this

Parshintseva, Jevgeni ; Kivilompolo, Maarit ; Ruiz-Jimenez, Jose ; Hartonen, Kari ; Kulmala, Markku ; Riekkola, Marja-Liisa. / Particle-into-liquid sampler on-line coupled with solid-phase extraction-liquid chromatography-mass spectrometry for the determination of organic acids in atmospheric aerosols. In: Journal of Chromatography A. 2010 ; Vol. 1217, No. 33. pp. 5427-5433.
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abstract = "In the present study, sample collection and preparation were directly integrated with a chromatographic system by coupling a particle-into-liquid sampler for the first time on-line with solid-phase extraction-liquid chromatography–tandem mass spectrometry. Several organic acids, such as adipic, hydroxyglutaric, mandelic, vanillic, cis-pinonic, pinic, azelaic and sebacic, were used in the research. For sample pretreatment and concentration, strong anion exchange material was used in the extraction. Sampling, extraction and analysis conditions were optimized to obtain reliable information about aerosol chemical composition. To evaluate the performance of the on-line coupled system, half of each sample was analysed on-line and the other half was derivatized and analysed off-line by gas chromatography–mass spectrometry. Comparison of the two techniques with use of t-test showed the results to be in an excellent agreement. Limits of detection of studied acids in on-line system were between 0.1 and 0.9 ng. The on-line coupled system is fast and reliable and a promising tool for the real time analysis of organic acids in atmospheric aerosols.",
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Particle-into-liquid sampler on-line coupled with solid-phase extraction-liquid chromatography-mass spectrometry for the determination of organic acids in atmospheric aerosols. / Parshintseva, Jevgeni; Kivilompolo, Maarit; Ruiz-Jimenez, Jose; Hartonen, Kari; Kulmala, Markku; Riekkola, Marja-Liisa (Corresponding Author).

In: Journal of Chromatography A, Vol. 1217, No. 33, 2010, p. 5427-5433.

Research output: Contribution to journalArticleScientificpeer-review

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T1 - Particle-into-liquid sampler on-line coupled with solid-phase extraction-liquid chromatography-mass spectrometry for the determination of organic acids in atmospheric aerosols

AU - Parshintseva, Jevgeni

AU - Kivilompolo, Maarit

AU - Ruiz-Jimenez, Jose

AU - Hartonen, Kari

AU - Kulmala, Markku

AU - Riekkola, Marja-Liisa

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N2 - In the present study, sample collection and preparation were directly integrated with a chromatographic system by coupling a particle-into-liquid sampler for the first time on-line with solid-phase extraction-liquid chromatography–tandem mass spectrometry. Several organic acids, such as adipic, hydroxyglutaric, mandelic, vanillic, cis-pinonic, pinic, azelaic and sebacic, were used in the research. For sample pretreatment and concentration, strong anion exchange material was used in the extraction. Sampling, extraction and analysis conditions were optimized to obtain reliable information about aerosol chemical composition. To evaluate the performance of the on-line coupled system, half of each sample was analysed on-line and the other half was derivatized and analysed off-line by gas chromatography–mass spectrometry. Comparison of the two techniques with use of t-test showed the results to be in an excellent agreement. Limits of detection of studied acids in on-line system were between 0.1 and 0.9 ng. The on-line coupled system is fast and reliable and a promising tool for the real time analysis of organic acids in atmospheric aerosols.

AB - In the present study, sample collection and preparation were directly integrated with a chromatographic system by coupling a particle-into-liquid sampler for the first time on-line with solid-phase extraction-liquid chromatography–tandem mass spectrometry. Several organic acids, such as adipic, hydroxyglutaric, mandelic, vanillic, cis-pinonic, pinic, azelaic and sebacic, were used in the research. For sample pretreatment and concentration, strong anion exchange material was used in the extraction. Sampling, extraction and analysis conditions were optimized to obtain reliable information about aerosol chemical composition. To evaluate the performance of the on-line coupled system, half of each sample was analysed on-line and the other half was derivatized and analysed off-line by gas chromatography–mass spectrometry. Comparison of the two techniques with use of t-test showed the results to be in an excellent agreement. Limits of detection of studied acids in on-line system were between 0.1 and 0.9 ng. The on-line coupled system is fast and reliable and a promising tool for the real time analysis of organic acids in atmospheric aerosols.

KW - On-line coupling

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KW - Organic acids

KW - Atmospheric aerosols

KW - HPLC-MS

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