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Advanced transportation biofuels have been the focus of intensive development since the early 2000s, and gasification in combination with synthesis technologies represents a flexible production pathway to deliver fuels for heavy-duty transport sectors that are difficult to electrify. This article is related to the pilot-scale development of a process concept aiming to smaller-scale production plants than are feasible with fluidized-bed gasifiers. Five test weeks with a total gasification time of 347 h were realized at a pilot plant that consisted of the pressurized staged fixed-bed gasifier, raw gas cooling to 500–600 °C, filtration with robust metal filters, and catalytic reforming of tars and methane. The gasifier combined an updraft primary stage and a catalytically enhanced secondary stage where most of the updraft tars were decomposed. The tar content of the product gas, 2–12 g/m3, was of the same order of magnitude as determined previously for fluidized-bed gasifiers. Consequently, similar filtration and reforming methods could be successfully applied. After the reformer, the contents of C2-hydrocarbon gases and high-molecular-weight tars were negligible.