Plant cell cultures of Nordic berry species: Phenolic and carotenoid profiling and biological assessments

Heiko Rischer; Liisa Nohynek; Riitta Puupponen-Pimiä; Joselin Aguiar; Gabriele Rocchetti; Luigi Lucini; José S. Câmara; Thiago Mendanha Cruz; Mariza Boscacci Marques; Daniel Granato

doi:10.1016/j.foodchem.2021.130571

Plant cell cultures of Nordic berry species: Phenolic and carotenoid profiling and biological assessments

Heiko Rischer^*, Liisa Nohynek, Riitta Puupponen-Pimiä, Joselin Aguiar, Gabriele Rocchetti, Luigi Lucini, José S. Câmara, Thiago Mendanha Cruz, Mariza Boscacci Marques, Daniel Granato^*

^*Corresponding author for this work

BA5306 Plant biotechnology

Research output: Contribution to journal › Article › Scientific › peer-review

17 Citations (Scopus)

Abstract

Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of flavones, phenolic acids, lignans, and total carotenoids, while CL, ST and SB presented the opposite behavior. AB and SB presented the lowest FRAP and CUPRAC values, while AB and CL presented the lowest reducing power. SB presented the lowest antioxidant activity measured by single electron transfer assays and the lowest content of lignans, phenolic acids, and flavones. CL and LI decreased the viability of in vitro mammary gland adenocarcinoma while only LI decreased the viability of in vitro lung carcinoma and showed protective effects of human erythrocytes against mechanical hemolysis.

Original language	English
Article number	130571
Number of pages	11
Journal	Food Chemistry
Volume	366
Early online date	10 Jul 2021
DOIs	https://doi.org/10.1016/j.foodchem.2021.130571
Publication status	Published - 1 Jan 2022
MoE publication type	A1 Journal article-refereed

Funding

This work was also supported by FCT-Fundação para a Ciência e a Tecnologia through the CQM Base Fund (UIDB/00674/2020, and Programmatic Fund - UIDP/00674/2020), and through Madeira 14-20 Program, project PROEQUIPRAM - Reforço do Investimento em Equipamentos e Infraestruturas Científicas na RAM (M1420-01-0145-FEDER-000008), and by ARDITI-Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação, through the project M1420-01-0145-FEDER-000005 - Centro de Química da Madeira - CQM+ (Madeira 14-20 Program).

Keywords

Antiproliferative activity
Food innovation
Food toxicology
Free radical scavengers
Functional foods
LC-MS
Phenolic composition

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.foodchem.2021.130571Licence: CC BY

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title = "Plant cell cultures of Nordic berry species: Phenolic and carotenoid profiling and biological assessments",

abstract = "Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of flavones, phenolic acids, lignans, and total carotenoids, while CL, ST and SB presented the opposite behavior. AB and SB presented the lowest FRAP and CUPRAC values, while AB and CL presented the lowest reducing power. SB presented the lowest antioxidant activity measured by single electron transfer assays and the lowest content of lignans, phenolic acids, and flavones. CL and LI decreased the viability of in vitro mammary gland adenocarcinoma while only LI decreased the viability of in vitro lung carcinoma and showed protective effects of human erythrocytes against mechanical hemolysis.",

keywords = "Antiproliferative activity, Food innovation, Food toxicology, Free radical scavengers, Functional foods, LC-MS, Phenolic composition",

author = "Heiko Rischer and Liisa Nohynek and Riitta Puupponen-Pimi{\"a} and Joselin Aguiar and Gabriele Rocchetti and Luigi Lucini and C{\^a}mara, {Jos{\'e} S.} and {Mendanha Cruz}, Thiago and {Boscacci Marques}, Mariza and Daniel Granato",

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doi = "10.1016/j.foodchem.2021.130571",

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T2 - Phenolic and carotenoid profiling and biological assessments

AU - Rischer, Heiko

AU - Nohynek, Liisa

AU - Puupponen-Pimiä, Riitta

AU - Aguiar, Joselin

AU - Rocchetti, Gabriele

AU - Lucini, Luigi

AU - Câmara, José S.

AU - Mendanha Cruz, Thiago

AU - Boscacci Marques, Mariza

AU - Granato, Daniel

PY - 2022/1/1

Y1 - 2022/1/1

N2 - Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of flavones, phenolic acids, lignans, and total carotenoids, while CL, ST and SB presented the opposite behavior. AB and SB presented the lowest FRAP and CUPRAC values, while AB and CL presented the lowest reducing power. SB presented the lowest antioxidant activity measured by single electron transfer assays and the lowest content of lignans, phenolic acids, and flavones. CL and LI decreased the viability of in vitro mammary gland adenocarcinoma while only LI decreased the viability of in vitro lung carcinoma and showed protective effects of human erythrocytes against mechanical hemolysis.

AB - Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of flavones, phenolic acids, lignans, and total carotenoids, while CL, ST and SB presented the opposite behavior. AB and SB presented the lowest FRAP and CUPRAC values, while AB and CL presented the lowest reducing power. SB presented the lowest antioxidant activity measured by single electron transfer assays and the lowest content of lignans, phenolic acids, and flavones. CL and LI decreased the viability of in vitro mammary gland adenocarcinoma while only LI decreased the viability of in vitro lung carcinoma and showed protective effects of human erythrocytes against mechanical hemolysis.

KW - Antiproliferative activity

KW - Food innovation

KW - Food toxicology

KW - Free radical scavengers

KW - Functional foods

KW - LC-MS

KW - Phenolic composition

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Plant cell cultures of Nordic berry species: Phenolic and carotenoid profiling and biological assessments

Abstract

Funding

Keywords

UN SDGs

Access to Document

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