TY - JOUR
T1 - Plant cell cultures of Nordic berry species
T2 - Phenolic and carotenoid profiling and biological assessments
AU - Rischer, Heiko
AU - Nohynek, Liisa
AU - Puupponen-Pimiä, Riitta
AU - Aguiar, Joselin
AU - Rocchetti, Gabriele
AU - Lucini, Luigi
AU - Câmara, José S.
AU - Mendanha Cruz, Thiago
AU - Boscacci Marques, Mariza
AU - Granato, Daniel
N1 - Funding Information:
This work was also supported by FCT-Fundação para a Ciência e a Tecnologia through the CQM Base Fund (UIDB/00674/2020, and Programmatic Fund - UIDP/00674/2020), and through Madeira 14-20 Program, project PROEQUIPRAM - Reforço do Investimento em Equipamentos e Infraestruturas Científicas na RAM (M1420-01-0145-FEDER-000008), and by ARDITI-Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação, through the project M1420-01-0145-FEDER-000005 - Centro de Química da Madeira - CQM+ (Madeira 14-20 Program). The continued efforts of Siv Matomaa, Kaisa Rinta-Harri, Tuuli Teikari and Jaana Rikkinen (all from VTT, Finland) are highly appreciated.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of flavones, phenolic acids, lignans, and total carotenoids, while CL, ST and SB presented the opposite behavior. AB and SB presented the lowest FRAP and CUPRAC values, while AB and CL presented the lowest reducing power. SB presented the lowest antioxidant activity measured by single electron transfer assays and the lowest content of lignans, phenolic acids, and flavones. CL and LI decreased the viability of in vitro mammary gland adenocarcinoma while only LI decreased the viability of in vitro lung carcinoma and showed protective effects of human erythrocytes against mechanical hemolysis.
AB - Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of flavones, phenolic acids, lignans, and total carotenoids, while CL, ST and SB presented the opposite behavior. AB and SB presented the lowest FRAP and CUPRAC values, while AB and CL presented the lowest reducing power. SB presented the lowest antioxidant activity measured by single electron transfer assays and the lowest content of lignans, phenolic acids, and flavones. CL and LI decreased the viability of in vitro mammary gland adenocarcinoma while only LI decreased the viability of in vitro lung carcinoma and showed protective effects of human erythrocytes against mechanical hemolysis.
KW - Antiproliferative activity
KW - Food innovation
KW - Food toxicology
KW - Free radical scavengers
KW - Functional foods
KW - LC-MS
KW - Phenolic composition
UR - http://www.scopus.com/inward/record.url?scp=85110545167&partnerID=8YFLogxK
U2 - 10.1016/j.foodchem.2021.130571
DO - 10.1016/j.foodchem.2021.130571
M3 - Article
C2 - 34284185
AN - SCOPUS:85110545167
VL - 366
JO - Food Chemistry
JF - Food Chemistry
SN - 0308-8146
M1 - 130571
ER -
