Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 433 - 440 |
| Number of pages | 8 |
| Journal | Trends in Plant Science |
| Volume | 9 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2004 |
| MoE publication type | A1 Journal article-refereed |
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Keywords
- metabolomics
- plant metabolites
- metabolites
- secondary metabolism
- secondary metabolites
- plants
Cite this
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Plant cell factories in the post-genomic era : New ways to produce designer secondary metabolites. / Oksman-Caldentey, Kirsi-Marja (Corresponding Author); Inze, Dirk.
In: Trends in Plant Science, Vol. 9, No. 9, 2004, p. 433 - 440.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Plant cell factories in the post-genomic era
T2 - New ways to produce designer secondary metabolites
AU - Oksman-Caldentey, Kirsi-Marja
AU - Inze, Dirk
PY - 2004
Y1 - 2004
N2 - Plants synthesize an extensive array of secondary metabolites, often with highly complex structures. Currently, most pharmaceutically important secondary metabolites are isolated from wild or cultivated plants because their chemical synthesis is not economically feasible. Biotechnological production in plant cell cultures is an attractive alternative, but to date this has had only limited commercial success because of a lack of understanding of how these metabolites are synthesized. Here, we discuss how the spectacular advances in plant genomics and metabolite profiling offer unprecedented possibilities to explore the extraordinary complexity of the plant biochemical capacity. State-of-the art genomics tools can be used to enhance the production of known target metabolites or to synthesize entire novel compounds by so-called combinatorial biochemistry in cultivated plant cells.
AB - Plants synthesize an extensive array of secondary metabolites, often with highly complex structures. Currently, most pharmaceutically important secondary metabolites are isolated from wild or cultivated plants because their chemical synthesis is not economically feasible. Biotechnological production in plant cell cultures is an attractive alternative, but to date this has had only limited commercial success because of a lack of understanding of how these metabolites are synthesized. Here, we discuss how the spectacular advances in plant genomics and metabolite profiling offer unprecedented possibilities to explore the extraordinary complexity of the plant biochemical capacity. State-of-the art genomics tools can be used to enhance the production of known target metabolites or to synthesize entire novel compounds by so-called combinatorial biochemistry in cultivated plant cells.
KW - metabolomics
KW - plant metabolites
KW - metabolites
KW - secondary metabolism
KW - secondary metabolites
KW - plants
U2 - 10.1016/j.tplants.2004.07.006
DO - 10.1016/j.tplants.2004.07.006
M3 - Article
VL - 9
SP - 433
EP - 440
JO - Trends in Plant Science
JF - Trends in Plant Science
SN - 1360-1385
IS - 9
ER -